Results 161 to 170 of about 32,714,285 (374)

Evaluation of bias induced by viral enrichment and random amplification protocols in metagenomic surveys of saliva DNA viruses [PDF]

open access: gold, 2018
Marcos Parras-Moltó   +3 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

PROTOCOL: Interventions for improving learning outcomes and access to education in low‐ and middle‐income countries: a systematic review

open access: yesCampbell Systematic Reviews, 2017
Birte Snilstveit   +8 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Evaluating Sex and Age Differences in ADI-R and ADOS Scores in a Large European Multi-site Sample of Individuals with Autism Spectrum Disorder [PDF]

open access: hybrid, 2018
Julian Tillmann   +27 more
openalex   +1 more source

Survey and Evaluation of RGB-D SLAM [PDF]

open access: gold, 2021
Shishun Zhang, Longyu Zheng, Wenbing Tao
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Methodological approaches to the choice of identification test methods for medicines

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The article summarises the main selective and non-selective methods of physical, chemical and physico-chemical analysis which are used in medicines identification testing and which differ in selectivity, sensitivity, informative value, sample preparation,
A. I. Lutseva   +10 more
doaj  

Cross-evaluation of modelled and remotely sensed surface soil moisture with in situ data in southwestern France [PDF]

open access: gold, 2010
Clément Albergel   +10 more
openalex   +1 more source

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