Results 91 to 100 of about 289,429 (265)

Detection of Security and Dependability Threats: A Belief Based Reasoning Approach [PDF]

, 2009
Monitoring the preservation of security and dependability (S&D) properties during the operation of systems at runtime is an important verification measure that can increase system resilience. However it does not always provide sufficient scope for taking
Lorenzoli, D., Spanoudakis, G.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

An Integrated Risk Assessment Framework for Construction Sites Using Pythagorean Fuzzy AHP and Classic/Fuzzy Fine-Kinney Method

IEEE Access
The construction industry demonstrates heightened occupational hazard exposure due to the confluence of multifaceted operational processes, variable workplace dynamics, and statistically significant accident occurrence rates. Effective risk assessment is
Mustafa Demirbilek, Sevim Ozulukale Demirbilek   +1 more
doaj   +1 more source

Tanzania Malaria Indicator Surveys 2001 - 2008:\ud Morbidity Indicators and Coverage of Major\ud Malaria Prevention and Control Interventions [PDF]

, 2010
Background\ud \ud Malaria continues to be a major public health problem in Africa. In Tanzania alone, thereare an estimated 17 to 20 million malaria cases per year resulting in approximately100,000 deaths.
Lengeler, Christian, Lottner,, Jeanne
core  

On Evidence-based Risk Management in Requirements Engineering

, 2017
Background: The sensitivity of Requirements Engineering (RE) to the context makes it difficult to efficiently control problems therein, thus, hampering an effective risk management devoted to allow for early corrective or even preventive measures ...
B Boehm, B Lawrence, BW Boehm, D Damian, D Karolak, D Méndez Fernández, D Méndez Fernández, D Méndez Fernández, D Méndez Fernández, M Felderer, M Kalinowski, R Wieringa, S Pfleeger, T DeMarco, T Gorschek, Y Asnar   +15 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Psychological well-being and factors affecting it after the COVID-19 pandemic

Frontiers in Psychology
IntroductionThe COVID-19 pandemic has enormously impacted human activity worldwide, partly due to many governments issuing stay-at-home orders and limiting the types of social interactions citizens can engage in.
Towhid Babazadeh, Saber Ghaffari-fam, Farzaneh Shahnavaz-Yoshanluie, Soheila Ranjbaran   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Relevance of a preventive model of osteomyoarticular lesions in young adults

Medisan
Introduction: Osteomyoarticular lesions among young people that render services for the defense are related to risk factors. The use of preventive models bases its approach on the identification of risk and development of actions for its prevention ...
Ernesto Sánchez Hernández, Gertrudis de la Torre Vega, Lisbet Estrada Ladoy, Mislay Rodríguez García, Nadina Travieso Ramos   +4 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source