Results 81 to 90 of about 167,990,442 (263)
Avaliação das ações de aconselhamento. Análise de uma perspectiva de prevenção centrada na pessoa
Cadernos de Saúde PúblicaEste trabalho apresenta a avaliação das ações de aconselhamento que se efetuam nos serviços do Sistema Único de Saúde (SUS) nos seguintes contextos institucionais: Centro de Testagem e Aconselhamento (CTA), Serviço de Assistência Especializada em HIV ...
Sandra Lúcia Filgueiras +1 more
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The assessment of occupational health service quality in Poland
Medycyna PracyBackground In the face of increasing problems related to lifestyle related diseases, attention is increasingly drawn to the untapped potential of the occupational health service (OHS) in undertaking preventive actions.
Agnieszka Lipińska-Ojrzanowska +3 more
doaj +1 more source
Postural defects in children and teenagers as one of the major issues in psychosomatic development
Pediatria i Medycyna Rodzinna, 2017 Postural defect is a set of postural abnormalities defined as minor single deviations from correct posture, which may be repaired with the use of appropriate exercises, passive or active.
Agata Wawrzyniak +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2014 The major goal of Phase II of this study was to collect and analyze much-needed descriptive, demographic, social, cultural, and clinical information about women receiving treatment in alcohol and substance abuse treatment centers funded in whole or in ...
University of California, San Francisco, Institute for Health Policy Studies, San Francisco, CA.
core
Evaluation of the ZIG-ZAIDS game: an entertaining educational tool for HIV/Aids prevention
Cadernos de Saúde PúblicaThis article presents the evaluation process for the ZIG-ZAIDS game, investigating the material's applicability in formal and informal educational contexts, i.e., how the game has been used by health professionals, parents, and the target population (pre-
Virgínia T. Schall +3 more
doaj
A Framework for Integrated Maintenance of a Multi-Robot Packaging Workcell
EngThe increasing deployment of collaborative and industrial robots in manufacturing systems places high demands on equipment reliability, availability, and maintenance efficiency. Robotic workcells, in which multiple automated subsystems operate in tightly
Daynier Rolando Delgado Sobrino +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source