Results 101 to 110 of about 167,990,442 (263)

Evaluation of the Indian Health Service Adolescent Regional Treatment Centers

, 2014
This study evaluated the effectiveness and efficiency of, and consumer satisfaction with, the nine regional treatment centers (RTC's) that provide alcoholism and substance abuse rehabilitation treatment to American Indian and Alaska Native youth.
Support Services, Inc., Silver Spring, MD.
core  

Quality assessment of IDRC evaluation reports [PDF]

, 2010
French version available in IDRC Digital Library: Appréciation de la qualité des rapports d'évaluation du CRDIIn order to monitor the quality of evaluation reports, and identify areas for improvement, IDRC’s Evaluation Unit conducts regular reviews of ...
IDRC. Evaluation Unit
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Risk assessment in miscellaneous food processing industries including producers of vegetables and spices [PDF]

, 2008
Risk Assessment of Microbial Problems and Preventive Actions in Food Industry - 2nd Open Seminar Arranged by SAFOODNET - Food Safety and Hygiene Networking Within New Member States and Associated Candidate Countries; Istanbul; Turkey; 22 October 2007 ...
Uyar, M. Fatih, Mokorel, Primoz, Korel, Figen, Güldaş, Metin, Ursu, Roxana, Lagouri, Vasiliki, Karpiskova, Renata, Lee, Solmaz, Kısıkkaya, N. Aslı, Türe, Hasan   +9 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Millimeter wave nondestructive evaluation of corrosion under paint in steel structures

, 2006
Millimeter wave nondestructive evaluation techniques have shown great potential for detection of corrosion under paint in steel structures. They may also provide for detection of other anomalies associated with the corrosion process such as precursor ...
Zoughi, Reza, Kharkovsky, Sergey N. (R16906)   +1 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

ASSESSMENT OF FACTORS RELATED TO COVID-19 PREVENTIVE HEALTH BEHAVIOURS USING A HEALTH BELIEF MODEL [PDF]

Publisher Copyright: © 2024 Sciendo. All rights reserved.Non-pharmaceutical interventions, including physical distancing, hand hygiene, mask wearing, are some of the most effective public health interventions against COVID-19 spread.
Krūmiņa, Valentīna, Perepjolkina, Viktorija, Mārtinsone, Kristīne   +2 more
core   +1 more source