Results 91 to 100 of about 121,838,606 (299)

Evaluation of a topical herbal patch for soft tissue wound healing: an animal study

open access: yesJournal of Clinical Periodontology, 2015
AbstractAimThis study evaluated the effects of a topical herbal patch (PerioPatch®) for gingival wound healing in a rat model.Materials and MethodsA mid‐crestal incision was performed on each side of the edentulous anterior maxilla in 48, 6‐month‐old, Wistar rats. Full‐thickness flaps were raised, repositioned and sutured. Four experimental groups were
Chaushu, Liat   +4 more
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

External review of the IDRC Evaluation Unit [PDF]

open access: yes, 2010
French version available in IDRC Digital Library: Constatations en bref de l'examen externe de la Section de l'évaluation du CRDIThis brief is based on the "Report on the 2010 External Review of the IDRC Evaluation Unit" by Ailish Byrne, Ian C.
IDRC. Evaluation Unit
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Composition Studies As A Creative Art

open access: yes, 1998
Bloom gathers twenty of her most recent essays (some previously unpublished) on critical issues in teaching writing. She addresses matters of philosophy and pedagogy, class and marginality and gender, and textual terror transformed to textual power.
LYNN Z. BLOOM, Bloom, Lynn Z.
core   +1 more source

Problems in Language Program Evaluation

open access: yes, 1994
Program evaluation on language programs. According tro Alderson (1986, p. 5), "evaluation is the process of seeking to establish the value of something for some purpose, a test is an instrument for gauging learning outcomes".
Brown, James Dean
core   +1 more source

Addressing Gaps in Educational Evaluation: A Comprehensive Meta-Analysis

open access: yesMimbar Ilmu
Educational evaluation plays a crucial role in ensuring the effectiveness of the learning process. However, various studies indicate gaps in the implementation of effective evaluation methods, such as the lack of a holistic approach and limited valid ...
Yoga Dwi Arianda   +2 more
doaj   +1 more source

Low Health Literacy and Evaluation of Online Health Information: A Systematic Review of the Literature

open access: yesJournal of Medical Internet Research, 2015
BackgroundRecent years have witnessed a dramatic increase in consumer online health information seeking. The quality of online health information, however, remains questionable.
Diviani, Nicola   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy