Results 111 to 120 of about 121,838,606 (299)
IEEE AccessTopic detection in social networks is extracting and summarizing frequent posts about an event or subject. Topic detection is a complex process and depends on language because it somehow needs to analyze text.
Elnaz Zafarani-Moattar +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Evaluation of topical metronidazole in the healing wounds process: an experimental study.
Revista do Colegio Brasileiro de Cirurgioes, 2011 To assess the efficacy of a topical 4% metronidazole solution in wound healing by secondary intention in rats.We made circular wounds two inches in diameter at the back of rats and studied healing at 3, 7, 14 and 21 days. The wound contraction and epithelialization were assessed by peripheral digital planimetry and myofibroblasts by ...
Lilian Cristine Teixeira, Trindade +5 more
openaire +1 more source
Gland SurgeryOral steroids are recommended as the first-line treatment for idiopathic granulomatous mastitis (IGM), but frequently induce significant side effects. Topical steroid therapy has recently emerged as a potential alternative for IGM, however current evidence regarding the efficacy of topical steroids remains scarce, primarily derived from small case ...
Lin, Weiyi +6 more
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
topicmodels: An R Package for Fitting Topic Models [PDF]
, 2011 Topic models allow the probabilistic modeling of term frequency occurrences in documents. The fitted model can be used to estimate the similarity between documents as well as between a set of specified keywords using an additional layer of latent ...
Kurt Hornik +3 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Research, demonstration, and evaluation studies.
Mode of access: Internet.Continued by: Research, demonstration, and evaluation studies, issued by: United States. Administration for Children, Youth, and Families.
United States. Office of Child Development. Research and Evaluation Division.
core
Annual corporate evaluation report 2010 [PDF]
, 2010 French version available in IDRC Digital Library: Rapport annuel sur l'évaluation 2010This report presents an in-depth analysis of selected evaluation topics, and notes the importance of the IDRC’s efforts in searching for improved approaches to ...
IDRC. Evaluation Unit
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source