Results 171 to 180 of about 308,468 (256)

Therapeutic Options in Refractory Evans Syndrome: A Case Report. [PDF]

open access: yesCureus, 2022
Jancar N   +4 more
europepmc   +1 more source

Case report: Refractory Evans syndrome in two patients with spondyloenchondrodysplasia with immune dysregulation treated successfully with JAK1/JAK2 inhibition. [PDF]

open access: yesFront Immunol, 2023
Gernez Y   +14 more
europepmc   +1 more source

Large‐Scale Psychometric Assessment and Validation of the Modified COVID‐19 Yorkshire Rehabilitation Scale Patient‐Reported Outcome Measure for Long COVID or Post‐COVID Syndrome

open access: yesJournal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT The C19‐YRS was the first condition‐specific for long COVID/post‐COVID syndrome. Although the original C19‐YRS evolved to the modified version (C19‐YRSm) based on psychometric evidence, clinical content relevance, as well as feedback from patients and healthcare professionals, it has not been validated through Rasch analysis. The study aim was
Mike Horton   +24 more
wiley   +1 more source

Metabolic syndrome and ADRB3 gene polymorphism in severely obese patients from South Italy [PDF]

open access: yes, 2007
C Finelli   +9 more
core  

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

open access: yesPediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak   +7 more
wiley   +1 more source

Conformational dynamics in insulin receptor kinase reveal a type III allosteric pocket

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Allosteric modulation is a promising strategy for selective kinase inhibition, yet structural insights into allosteric pockets remain limited across the human kinome. In this work, we present comprehensive characterization of a type III allosteric pocket in the insulin receptor kinase (IRK), integrating structural, conformational, and ...
Jyoti Verma, Harish Vashisth
wiley   +1 more source

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