Results 11 to 20 of about 4,455,205 (312)
Clinical Medicine Insights: Case Reports, 2023 This case report describes a 23-year-old male patient who presented with right chylothorax as the initial manifestation of a severe flare of systemic lupus erythematosus (SLE) and secondary Evans syndrome.
David Corredor-Orlandelli +3 more
doaj +2 more sources
Naproxen-Induced Evans Syndrome
Cureus, 2023 Evans syndrome is an autoimmune disorder characterized by the simultaneous occurrence of autoimmune hemolytic anemia and immune thrombocytopenic purpura. It can further be classified as primary Evans syndrome when it occurs by itself, or secondary Evans syndrome when it is associated with other autoimmune and lymphoproliferative disorders ...
Ahoussougbemey Mele, Ange +4 more
openaire +3 more sources
La Pediatria Medica e Chirurgica, 2014 We describe a case of a 14-years old caucasian female affected by autoimmune hemolytic anemia and thrombocytopenia successfully treated with intravenous immunoglobulin and steroids. Nevertheless, neutropenia occurred during follow-up period.
F. Porcaro +9 more
doaj +5 more sources
Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus
Journal of Experimental MedicineExome sequencing in pediatric systemic lupus and Evans syndrome identified six novel monoallelic PTPN2 mutations, impairing its regulatory function. This caused T cell hyperproliferation and high inflammatory cytokines, highlighting the druggable JAK ...
Frédéric Rieux-Laucat +2 more
exaly +2 more sources
Case Report: Native aortic valve Listeria monocytogenes endocarditis in an adult with Evans syndrome [PDF]
Frontiers in ImmunologyBackgroundListeria monocytogenes is an uncommon cause of infective endocarditis but is associated with a high morbidity and mortality rate in immunocompromised hosts.
Chen-Yu Wei +10 more
doaj +2 more sources
Frontiers in Immunology, 2021 Background Tuberculosis (TB) is a leading cause of morbidity and mortality in underdeveloped and developing countries. Disseminated TB may induce uncommon and potentially fatal secondary hemophagocytic lymphohistiocytosis (HLH).
Benquan Wu, Yunfeng Shi
exaly +2 more sources
Anti-CD19 chimeric antigen receptor T cells in Evans syndrome of systemic lupus erythematosus [PDF]
Annals of HematologyEvans syndrome, characterized by autoimmune hemolytic anemia and immune thrombocytopenia, is rare and often refractory to conventional therapies. In Chinese patients with systemic lupus erythematosus (SLE), its incidence is approximately 0.47%. We report
Min Lang +6 more
doaj +2 more sources
Platelets, 2022 Treatment of refractory autoimmune cytopenias (AICs) and Evans syndrome (ES) represent a great challenge in pediatric setting, where an underlying primary immunodeficiency is recurrent.
Francesca Conti +8 more
doaj +2 more sources
Evans syndrome in adults: an observational multicenter study [PDF]
Blood Advances, 2021 Abstract Evans syndrome (ES) is a rare condition, defined as the presence of 2 autoimmune cytopenias, most frequently autoimmune hemolytic anemia and immune thrombocytopenia (ITP) and rarely autoimmune neutropenia. ES can be classified as primary or secondary to various conditions, including lymphoproliferative disorders, other systemic ...
Bruno Fattizzo +20 more
openaire +9 more sources
Severe relapse of Evans syndrome in an adult patient with treatment resistance and fatal outcome: A case report [PDF]
Journal of International Medical ResearchEvans syndrome is an uncommon autoimmune disorder characterized by autoimmune hemolytic anemia and immune thrombocytopenia. It can follow a relapsing course in adults and may be challenging to treat.
Amr R Saleh +3 more
doaj +2 more sources