Results 81 to 90 of about 303,442 (283)

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

open access: yesFood Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee   +4 more
wiley   +1 more source

A strange case of Evans syndrome

open access: yesItalian Journal of Medicine, 2013
Evans syndrome is a rare autoimmune disease presenting hemolytic anemia, thrombocytopenia and/or neutropenia. It may be associated with other autoimmune or lymphoproliferative diseases.
Manuel Monti   +5 more
doaj   +1 more source

Sleep Problems in Children With Autism Spectrum Disorder [PDF]

open access: yes, 2020
The purpose of the current study was to examine the effect of restricted and repetitive behaviors (RRBs) on the relationship between sleep problems and externalizing behaviors in young children with autism spectrum disorder (ASD).
Alba, Laura A
core  

Does Metformin combined with Clomiphene Citrate improve fertility related outcomes in Clomiphene resistant women with PCOS : a systematic review [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Colleran, Rebecca   +5 more
core   +2 more sources

Pregnancy and Evans´ syndrome: case report

open access: yesHorizonte Médico, 2015
Evans´ syndrome is the coexistence of autoimmune thrombocytopenia with autoimmune hemolytic anemia. It is rarely found during the course of a pregnancy. This makes treatment options more difficult, since some therapeutic drugs are teratogenic.
Santiago Artucio   +4 more
doaj  

Meier–Gorlin syndrome and Wolf–Hirschhorn syndrome: two developmental disorders highlighting the importance of efficient DNA replication for normal development and neurogenesis [PDF]

open access: yes, 2013
Microcephaly represents one of the most obvious clinical manifestations of impaired neurogenesis. Defects in the DNA damage response, in DNA repair, and structural abnormalities in centrosomes, centrioles and the spindle microtubule network have all been
Abramowicz, Iga   +4 more
core   +1 more source

Understanding the associations between neurodevelopmental features and internalising and externalising behaviours: A transdiagnostic approach

open access: yesJCPP Advances, EarlyView.
Abstract Background Internalising and externalising behaviours—significant markers for lifetime psychiatric vulnerability—are elevated in children with neurodevelopmental diagnoses, including autism. Although neurodevelopmental features of autism are dimensions that span the population, limited research has examined their differential patterns of ...
Sarah J. Carrington   +5 more
wiley   +1 more source

GABAB receptor ligands for the treatment of alcohol use disorder: preclinical and clinical evidence. [PDF]

open access: yes, 2014
The present paper summarizes the preclinical and clinical studies conducted to define the "anti-alcohol" pharmacological profile of the prototypic GABAB receptor agonist, baclofen, and its therapeutic potential for treatment of alcohol use disorder (AUD).
Agabio R, Colombo G
core   +2 more sources

Potentially morally injurious events and posttraumatic stress symptom change across the military‐to‐civilian transition: A prospective study

open access: yesJournal of Traumatic Stress, EarlyView.
Abstract This prospective study examined whether exposure to potentially morally injurious events (PMIEs), specifically self‐attributed transgressions, other‐attributed transgressions, and experiences of betrayal, predicted change in posttraumatic stress symptoms (PTSS) and reintegration difficulty during the military‐to‐civilian transition (MCT). U.S.
Walter J. Sowden   +2 more
wiley   +1 more source

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