Results 51 to 60 of about 50,299 (283)

Nondominated Maneuver Strategy Set With Tactical Requirements for a Fighter Against Missiles in a Dogfight

open access: yesIEEE Access, 2020
Dogfight is often a continuous and multi-round process with missile attacks. If the fighter only considers the security when evading the incoming missile, it will easily lose the superiority in subsequent air combat.
Zhen Yang   +5 more
doaj   +1 more source

Incorporation of Modeling, Simulation, and Game-Based Learning in Engineering Dynamics Education towards Improving Vehicle Design and Driver Safety

open access: yesSafety, 2021
As educational tools continue to evolve technologically, game-based learning (GBL) has emerged for its ability to improve specific learning outcomes such as motivation, engagement, and knowledge acquisition and retention.
Kevin F. Hulme   +4 more
doaj   +1 more source

Evasive maneuver subsequent to CSM/LM ejection from the S-4B in earth orbit - Project Apollo [PDF]

open access: yes, 1969
Apollo 9 evasive maneuver after command service module/lunar module ejection from Saturn S-4B stage in earth ...
Donahoo, M. E., Fraley, C. W.
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

HSV.com: Maneuvering the internetworks of viral neuropathogenesis and evasion of the host defense [PDF]

open access: yesProceedings of the National Academy of Sciences, 2000
The combination of viral genetics and animal knockout technologies enables one to define precise molecular pathways and targets of specific viral virulence and/or host defense genes. The dual genetic knockout paper in this issue of PNAS (1) exemplifies this concept. Leib and coworkers provide convincing in vivo evidence supporting a previously proposed
S L, Tan, M G, Katze
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Application of MEMS Sensors for Evaluation of the Dynamics for Cargo Securing on Road Vehicles

open access: yesSensors, 2021
Safety is one of the key aspects of the successful transport of cargo. In the case of road transport, the dynamics of a vehicle during normal events such as braking, steering, and evasive maneuver are variable in different places in the vehicle.
Jozef Gnap   +4 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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