Results 91 to 100 of about 8,541,152 (269)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

METODE KONVENSIONAL DAN INKONVENSIONAL DALAM PEMBELAJARAN BAHASA ARAB

Jurnal Ilmiah Didaktika: Media Ilmiah Pendidikan dan Pengajaran, 2012
In the Arabic language learning, the method has a very significant position to achieve the goal. If so, then the method must exist on each of the learning process conducted by a teacher or educator.
Sahkholid Nasution
doaj   +1 more source

Even Kinship Terminology, Society and Language Contact

Journal of Language Contact
Abstract The paper analyses on the basis of new fielddata the transformations of kinship terminologies in three Even dialects which have come about through cultural and linguistic contacts. We investigate two possible sources of change. First, the adaptation of kinship terminology to the ways of subsistence, such that, e.g., hunting and gathering ...
Lavrillier, Alexandra, Matić, Dejan
openaire   +2 more sources

Learning deterministic even linear languages from positive examples

Theoretical Computer Science, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Takeshi Koshiba, Erkki Mäkinen, Yuji Takada   +2 more
openaire   +3 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

A Blessing in Disguise: Flanking Words Can Cancel Language Switch Costs

Journal of Cognition
Prior research has shown that a sentence context can decrease the necessity for language control relative to single word processing. In particular, measures of language control such as language switch costs are reduced or even absent in a sentence ...
Aaron Vandendaele, Nicoleta Prutean, Mathieu Declerck   +2 more
doaj   +1 more source

SYNTACTIC FEATURES IN THE VERKHNEKOLYMSKIУ DIALECT OF THE EVEN LANGUAGE

Theoretical and Applied Linguistics, 2019
The article discusses the syntactic features in the Verkhnekolymsky dialect of the Even language, which has not been coherently described so far. The analysis of the material collected during the field expedition to the Verkhnekolymsky region of the Sakha Republic (Yakutia) in 2014 enabled to state that the word order in Verkhnekolymsky dialect is ...
openaire   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source