Results 51 to 60 of about 955,872 (288)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
, 2014 Pite Saami is a highly endangered Western Saami language in the Uralic language family currently spoken by a few individuals in Swedish Lapland. This grammar is the first extensive book-length treatment of a Saami language written in English.
Wilbur, Joshua; University of Freiburg
core +1 more source
La « Harangue faicte au Roy par Itapoucou » : un discours politique en langue tupi (France, XVIIe)
Corpus: Archivos Virtuales de la Alteridad Americana, 2014 The speech addressed to king of France Louis XIII, in 1614, by an Indian from Maragnan as ambassador, allows us to observe the language and rhetoric tupi of this distant time, and especially to study the way this text in original language takes place in ...
Géraldine Méret
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Modalidade e modo em português europeu
Este livro oferece uma apresentação dos sistemas da modalidade e do modo em Português Europeu. A aproximação aos temas abordados tem por base o espírito da semântica formal, mas a apresentação é informal, sendo o texto acessível a qualquer leitor, mesmo ...
Marques, Rui; University of Macau
core +6 more sources
Serawai sebagai bahasa minoritas (sebuah kajian ekolinguistik dalam pembelajaran dan pemertahanan)
DiglosiaThe purpose of this research is to analyze the role of the environment in the learning and preservation of the Serawai language, also known as ecolinguistics.
Andestend Andestend +3 more
doaj +1 more source
Word order variation in Plautus
Linguistica, 2005 Unlike some other language phenomena, word order is an unavoidable feature of an utterance. It can be observed in any language as it is always necessary to arrange words (provided the language in question discerns such meaningful entities) in some ...
Matjaž Babič
doaj +1 more source