Results 151 to 160 of about 108,897 (285)

Even evenness is important: the direct and mediating effects of species abundances for ecosystem services. [PDF]

New Phytol
Hordijk I.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Multiple Community Properties Drive Ecosystem Resistance and Resilience to Extreme Climate Events Across Mesic Grasslands. [PDF]

Ecol Lett
Ajowele JA, Darst AL, Baker NR, Brenneman RR, Broderick C, Cappelli SL, Liang M, Linabury M, Nieland MA, Parker-Smith M, Limbu SP, Terry RS, Young ML, Zaret M, Zaricor M.   +14 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Influences of Structural and Species Diversity on Forest Resistance to Drought. [PDF]

Ecol Lett
Crockett ETH, Guo Q, Atkins JW, Sun G, Potter KM, Costanza JK, Ollinger SV, Woodall CW, McNulty S, Trettin C, Holgerson J, Xiao J.   +11 more
europepmc   +1 more source

WISER Deliverable D3.1-2: Report on phytoplankton bloom metrics [PDF]

, 2011

core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Stool Dynamics and the Developing Gut Microbiome During Infancy. [PDF]

J Biol Rhythms
Al-Andoli M, Schoch S, Markovic A, Mühlematter C, Beaugrand M, Jenni OG, Liamlahi R, Walser JC, Nielsen D, Kurth S.   +9 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Linking Grassland Canopy Structure and Function Responses to Field Experimental Drought Both Seasonally and Interannually. [PDF]

Ecol Evol
Encarnación Ojeda M, Xiao X, Nguyen EU, Souza L.   +3 more
europepmc   +1 more source