Results 151 to 160 of about 396,760 (264)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Patient involvement in the development of childhood, adolescent and young adult cancer survivorship guidelines: recommendations from EU-CAYAS-NET ambassadors. [PDF]

Res Involv Engagem
Wams J, Hartogh JD, Gsell H, Schneider C, Brunmair B, Zettl A, Tomášiková Z, Kienesberger A, Rizvi K, Totovina AM, Skinner R, Dorsthorst JT, der Pal HJHV, Kremer LCM, van Dalen EC, Mulder RL, EU-CAYAS-NET ambassadors and consortium.   +16 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Cutaneous Leukocytoclastic Vasculitis as a rare adverse event of infliximab in Crohn's disease: a case report. [PDF]

Oxf Med Case Reports
El Mourad H, Alsayed E, Al Doheyan T, Alomar Y, Alharbi O.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Community engagement and involvement in Sri Lanka: a knowledge mobilisation case study. [PDF]

Res Involv Engagem
Wimalasekera M, Blackburn S, Arachchi RW, Jayasinghe C, Guruge GND, Higginbottom A, Jayasinghe OS, Jabir S, Samarakkody V, Opatha J, Dissanayake L, Jayaweera K, Wickramasinghe E, Hewamalage A, Fernando B, Alwis S, Kodituwakku G, Abeysinghe N, Zavos H, Dziedzic K, Sumathipala A.   +20 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Consensus Guidelines for the Management of Tissue Filler-Induced Vision Loss in the United Kingdom. [PDF]

Aesthet Surg J
Sansome S, Clague M, Convery C, Davies E, Fairris C, Goodman G, Harris S, Hawkes E, Hay G, Murray G, Shah-Desai S, Vize C, Walker L, Neffendorf JE.   +13 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Cardiac lipoma of the right atrial appendage: Multimodality imaging of a rare tumor at an uncommon site. [PDF]

Radiol Case Rep
Kosum P, Tumkosit M, Jarutasnangkul L, Chantranuwatana P, Pakdeepaithun A, Tanangterapong P, Theerasuwipakorn N.   +6 more
europepmc   +1 more source