Results 161 to 170 of about 396,760 (264)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Unmasking the appeal: voices of young adults prior to World No Tobacco Day at Qatar University. [PDF]

Front Public Health
Alyafei O, Al-Shafai S, Al-Mansouri S, Abouzoor R, Al-Hamdani M.   +4 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Frequency and associated factors of herpes zoster infection in SLE patients from Latin America: data from the GLADEL 2.0 cohort. [PDF]

Lupus Sci Med
Nieto R, Hernández L, Scolnik M, Maurelli L, Gobbi C, Saurit V, Garcia L, Kisluk B, Bertolaccini MC, Serna Góngora M, Gómez GN, Pisoni C, Ralle AC, Pirruccio P, de Souza Barbosa V, Gasparin A, Duarte A, Alves Alvino LC, Borba EF, Bonfá E, Reis-Neto ETD, Bondi Peralta A, Massardo L, Aroca Martínez G, Iglesias Gamarra A, Cañas CA, Quintana López G, Frederick Silvery L, Martinez JM, Sánchez-Briones R, Pérez Cristóbal M, Martín-Nares E, Silveira LH, García De La Torre I, Ramírez Sánchez JC, Esquivel-Valerio JA, Losanto J, Vazquez MA, Linares MA, Ugarte-Gil MF, Calvo-Quiroz A, Polanco T, Pizzarossa C, Silveira G, Pons-Estel BA, Alarcon GS, Pons-Estel G.   +46 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Primary intracranial Ewing-like sarcoma presenting with rapid bilateral blindness: A case report. [PDF]

Radiol Case Rep
Guerrouaz MA, Berhili S, Moukhlissi M, Bahhous K, Mezouar L.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The Impact of Vascular Management on Postoperative Complications in Patients Undergoing Surgery for Retroperitoneal Leiomyosarcoma. [PDF]

Curr Oncol
Malik N, Kim S, Scally CP, Keung EZ, Lillemoe H, Torres KE, Hunt KK, Khan S, Roland CL, Lyu HG.   +9 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Differential motor signatures in isolated and narcolepsy-related REM sleep behaviour disorder: a preliminary study. [PDF]

Front Neurol
Drakatos P, Duncan I, Wasserman D, Gnoni V, O'Regan D, Varga AW, Tan H, Ashkan K, Grinberg LT, Parrino L, Ferini-Strambi L, Goadsby PJ, Chaudhuri KR, Rosenzweig I.   +13 more
europepmc   +1 more source