Results 41 to 50 of about 16,614 (261)

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Scintillation in Low-Temperature Particle Detectors

Physics, 2021
Inorganic crystal scintillators play a crucial role in particle detection for various applications in fundamental physics and applied science. The use of such materials as scintillating bolometers, which operate at temperatures as low as 10 mK and detect
Denys Poda
doaj   +1 more source

Interpretable Joint Event-Particle Reconstruction for Neutrino Physics at NOvA with Sparse CNNs and Transformers

, 2023
The complex events observed at the NOvA long-baseline neutrino oscillation experiment contain vital information for understanding the most elusive particles in the standard model. The NOvA detectors observe interactions of neutrinos from the NuMI beam at Fermilab. Associating the particles produced in these interaction events to their source particles,
Shmakov, Alexander, Yankelevich, Alejandro, Bian, Jianming, Baldi, Pierre   +3 more
openaire   +2 more sources

Developing and Evaluating a Laboratory‐Based Frailty Index (FI‐Lab) for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Event generators for high-energy physics experiments

SciPost Physics
We provide an overview of the status of Monte-Carlo event generators for high-energy particle physics. Guided by the experimental needs and requirements, we highlight areas of active development, and opportunities for future improvements.
J. M. Campbell, M. Diefenthaler, T. J. Hobbs, S. Höche, J. Isaacson, F. Kling, S. Mrenna, J. Reuter, S. Alioli, J. R. Andersen, C. Andreopoulos, A. M. Ankowski, E. C. Aschenauer, A. Ashkenazi, M. D. Baker, J. L. Barrow, M. van Beekveld, G. Bewick, S. Bhattacharya, C. Bierlich, E. Bothmann, P. Bredt, A. Broggio, A. Buckley, A. Butter, J. M. Butterworth, E. P. Byrne, C. M. Carloni-Calame, S. Chakraborty, X. Chen, M. Chiesa, J. T. Childers, J. Cruz-Martinez, J. Currie, N. Darvishi, M. Dasgupta, A. Denner, F. A. Dreyer, S. Dytman, B. K. El-Menoufi, T. Engel, S. Ferrario Ravasio, D. Figueroa, L. Flower, J. R. Forshaw, R. Frederix, A. Friedland, S. Frixione, H. Gallagher, K. Gallmeister, S. Gardiner, R. Gauld, J. Gaunt, A. Gavardi, T. Gehrmann, A. Gehrmann-De Ridder, L. Gellersen, W. Giele, S. Gieseke, F. Giuli, E. W. N. Glover, M. Grazzini, A. Grohsjean, C. Gütschow, K. Hamilton, T. Han, R. Hatcher, G. Heinrich, I. Helenius, O. Hen, V. Hirschi, M. Höfer, J. Holguin, A. Huss, P. Ilten, S. Jadach, A. Jentsch, S. P. Jones, W. Ju, S. Kallweit, A. Karlberg, T. Katori, M. Kerner, W. Kilian, M. M. Kirchgaeßer, S. Klein, M. Knobbe, C. Krause, F. Krauss, J. Lang, J. -N. Lang, G. Lee, S. W. Li, M. A. Lim, J. M. Lindert, D. Lombardi, L. Lönnblad, M. Löschner, N. Lurkin, Y. Ma, P. Machado, V. Magerya, A. Maier, I. Majer, F. Maltoni, M. Marcoli, G. Marinelli, M. R. Masouminia, P. Mastrolia, O. Mattelaer, J. Mazzitelli, J. McFayden, R. Medves, P. Meinzinger, J. Mo, P. F. Monni, G. Montagna, T. Morgan, U. Mosel, B. Nachman, P. Nadolsky, R. Nagar, Z. Nagy, D. Napoletano, P. Nason, T. Neumann, L. J. Nevay, O. Nicrosini, J. Niehues, K. Niewczas, T. Ohl, G. Ossola, V. Pandey, A. Papadopoulou, A. Papaefstathiou, G. Paz, M. Pellen, G. Pelliccioli, T. Peraro, F. Piccinini, L. Pickering, J. Pires, W. Placzek, S. Plätzer, T. Plehn, S. Pozzorini, S. Prestel, C. T. Preuss, A. C. Price, S. Quackenbush, E. Re, D. Reichelt, L. Reina, C. Reuschle, P. Richardson, M. Rocco, N. Rocco, M. Roda, A. Rodriguez Garcia, S. Roiser, J. Rojo, L. Rottoli, G. P. Salam, M. Schönherr, S. Schuchmann, S. Schumann, R. Schürmann, L. Scyboz, M. H. Seymour, F. Siegert, A. Signer, G. Singh Chahal, A. Siódmok, T. Sjöstrand, P. Skands, J. M. Smillie, J. T. Sobczyk, D. Soldin, D. E. Soper, A. Soto-Ontoso, G. Soyez, G. Stagnitto, J. Tena-Vidal, O. Tomalak, F. Tramontano, S. Trojanowski, Z. Tu, S. Uccirati, T. Ullrich, Y. Ulrich, M. Utheim, A. Valassi, A. Verbytskyi, R. Verheyen, M. Wagman, D. Walker, B. R. Webber, L. Weinstein, O. White, J. Whitehead, M. Wiesemann, C. Wilkinson, C. Williams, R. Winterhalder, C. Wret, K. Xie, T-Z. Yang, E. Yazgan, G. Zanderighi, S. Zanoli, K. Zapp
doaj   +1 more source

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

International Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg, Paulo Jefferson Dias de Oliveira Evald, Shivam Chaturvedi, Hilton Abilio Gründling, Rodrigo Varella Tambara, Wencong Su   +5 more
wiley   +1 more source

Machine Learning Approach for Event Position Reconstruction in the DEAP-3600 Dark Matter Search Experiment

Physics, 2023
In addition to classical analytical data processing methods, machine learning methods are widely used for data analysis in elementary particle physics.
DEAP Collaboration
doaj   +1 more source

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

Advanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi, Pasquale Guglielmi, Gianfranco Palumbo, Giuseppe Carbone   +3 more
wiley   +1 more source

A likelihood framework for cryogenic scintillating calorimeters used in the CRESST dark matter search

European Physical Journal C: Particles and Fields
Cryogenic scintillating calorimeters are ultra- sensitive particle detectors for rare event searches, particularly for the search for dark matter and the measurement of neutrino properties.
CRESST Collaboration, G. Angloher, S. Banik, G. Benato, A. Bento, A. Bertolini, R. Breier, C. Bucci, J. Burkhart, L. Canonica, A. D’Addabbo, S. Di Lorenzo, L. Einfalt, A. Erb, F. v. Feilitzsch, S. Fichtinger, D. Fuchs, A. Garai, V. M. Ghete, P. Gorla, P. V. Guillaumon, S. Gupta, D. Hauff, M. Ješkovský, J. Jochum, M. Kaznacheeva, A. Kinast, H. Kluck, H. Kraus, S. Kuckuk, A. Langenkämper, M. Mancuso, L. Marini, B. Mauri, L. Meyer, V. Mokina, M. Olmi, T. Ortmann, C. Pagliarone, L. Pattavina, F. Petricca, W. Potzel, P. Povinec, F. Pröbst, F. Pucci, F. Reindl, J. Rothe, K. Schäffner, J. Schieck, D. Schmiedmayer, S. Schönert, C. Schwertner, M. Stahlberg, L. Stodolsky, C. Strandhagen, R. Strauss, I. Usherov, F. Wagner, V. Wagner, V. Zema   +59 more
doaj   +1 more source