Results 131 to 140 of about 19,209,348 (309)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Testing the Event Visibility Hypothesis in Austrian Sign Language (ÖGS)

Language and Cognition
In sign languages, aspects of event structure have been shown to be systematically reflected in the phonological structure of verb signs, as proposed by the Event Visibility Hypothesis (EVH).
Julia Krebs, Ronnie B. Wilbur, Evie A. Malaia   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Transitivity and self-caused readings in Spanish deverbal nouns

Linguistica Brunensia, 2017
This paper examines the structural properties underlying the distribution and interpretation of two types of deverbal nouns in Spanish: miento nominals (e.g. hundimiento 'the sinking') and do/da nominals (e.g.
Natalia Jardón
doaj  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Spatial structures in event-place formation

Journal of Architecture and Urbanism
Event-places occupy different physical layouts, but we lack a comprehensive understanding of their structures and arrangements. This study aims to uncover some of these patterns by examining various urban spaces recognized as event-places.
Manoochehr Moazzami, Faezeh Tafreshi
doaj   +1 more source

Using Event Structure Analysis to Understand Planned Social Change

International Journal of Qualitative Methods, 2003
In this article, the authors explore the application of Event Structure Analysis in understanding the linkages between events in planned social change.
William Stevenson, Heidi Zinzow, Sanjeev Sridharan   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Aspectual Properties of Italian Venire Passives

Isogloss
Italian essere (be) and venire (come) periphrastic passives differ in their aspectual properties, both lexical and grammatical. Squartini’s (1999) analysis of venire passives accounts for their incompatibility with perfect aspect.
Martine Gallardo
doaj   +1 more source