Results 131 to 140 of about 15,467,810 (252)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Women\u27s Studies Newsletter 2000-2001. [PDF]
, 2001 Women\u27s Studies newsletter recaps some of the department\u27s annual news and events, introduces faculty and students and notes upcoming ...
SFU Women\u27s Studies Department +1 more
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
BLOG: HSA Sponsored Event - the Immigration Act and Public Services
, 2018 First paragraph: On June 8th Dr Kim McKee (University of St Andrews) and Dr Sharon Leahy (University of St Andrews) hosted a symposium on ‘The Impact of the UK Immigration Act on Housing and Public Services’ at the University of St Andrews. The event was
Leahy, Sharon, McKee, Kim
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Perspective (Institute for Christian Studies)
, 1996 Three new faculty appointments spark excitement [Adrienne Dengerink Chaplin; Carroll Guen Hart; Douglas Blomberg], From the President: Short Catechism [roots of the Institute’s Reformed vision of Education], Students [M. Phil. F.
Fernhout, Harry +2 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
EPISTEMOLOGY, TRANSLATION AND A PATH FOR MEANING
Mutatis Mutandis, 2012 : Basically, this essay traces an epistemological line. It starts by mentioning how positivism has influenced thought and knowledge today, especially in the field of Translation Studies.
Heidy Gutierrez
doaj