Results 121 to 130 of about 74,688 (254)

Efficacy of everolimus plus octreotide LAR in patients with advanced neuroendocrine tumor and carcinoid syndrome: final overall survival from the randomized, placebo-controlled phase 3 RADIANT-2 study [PDF]

, 2019
Marianne Pavel, E. Baudin, Kjell E. Öberg, J.D. Hainsworth, M. Voi, N. Rouyrre, M. Peeters, D.J. Gross, J.C. Yao   +8 more
openalex   +1 more source

Pediatric Investigation Plans for seizure and epilepsy treatments: An analysis since the implementation of the European Pediatric Regulation in 2006

Epilepsia, EarlyView.
Abstract Objective A Pediatric Investigation Plan (PIP) implemented under the European Pediatric Regulation (EC No. 1901/2006) aims to ensure early and systematic evaluation of medicines for children. We analyze PIPs for antiseizure medications (ASMs) submitted to the European Medicines Agency (EMA) since 2006, characterizing their content, focusing on
Valeria Agostini, Stéphane Auvin
wiley   +1 more source

Analysis of early use of everolimus with low-dose calcineurin inhibitors in kidney transplant recipient

Вестник трансплантологии и искусственных органов, 2019
Aim: to evaluate the efficacy and safety of early use of everolimus in combination with a reduced dose of calcineurin inhibitors (CNI) after kidney transplantation and define approaches to the selection and management of patients on everolimus-based ...
I. G. Kim, N. A. Tomilina, I. V. Ostrovskaya, I. A. Skryabina, N. D. Fedorova   +4 more
doaj   +1 more source

Mid-term Safety and Efficacy of Absorb Bioresorbable Vascular Scaffold Versus Everolimus-Eluting Metallic Stent: A Meta-Analysis [PDF]

, 2017
F. Ha, Nitesh Nerlekar, James D. Cameron, Martin R. Bennett, Ian T. Meredith, Nick E.J. West, Adam J. Brown   +6 more
openalex   +1 more source

Repurposing Verapamil to Enhance Killing of T-ALL Cells by the mTOR Inhibitor Everolimus [PDF]

, 2023
Micol Silic‐Benussi, Evgeniya Sharova, Alberto Corradin, Loredana Urso, Vittoria Raimondi, Ilaria Cavallari, Barbara Buldini, Samuela Francescato, Sonia Minuzzo, Donna M. D’Agostino, Vincenzo Ciminale   +10 more
openalex   +1 more source

Clinical trajectories and medication response in TBC1D24‐related epilepsies

Epilepsia, EarlyView.
Abstract Objective Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24‐related disorders.
Ealing Mondragon, Jan H. Magielski, Bintou Bane, JoeyLynn Nolan, Sarah M. Ruggiero, Dallas Armstrong, Susan Arnold, Deepa Sirsi, Ingo Helbig, Jillian L. McKee   +9 more
wiley   +1 more source

Phase I-II study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer

BMC Cancer, 2011
Background For patients with metastatic renal cell cancer (mRCC) who progressed on vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor therapy, the orally administered mammalian target of rapamycin (mTOR) inhibitor everolimus has
Huijts Charlotte M, Santegoets Saskia J, van den Eertwegh Alfons J, Pijpers Laura S, Haanen John B, de Gruijl Tanja D, Verheul Henk M, van der Vliet Hans J   +7 more
doaj   +1 more source

Clinical outcomes following stereotactic MRI‐guided laser ablation in children with tuberous sclerosis complex and intractable epilepsy

Epilepsia, EarlyView.
Abstract Objective In children with tuberous sclerosis complex (TSC) and drug‐resistant epilepsy (DRE), magnetic resonance imaging–guided stereotactic laser ablation (SLA) therapy offers less‐invasive treatment compared to craniotomy and resection. Our study seeks to further expand on the long‐term outcomes in patients with TSC‐related DRE who have ...
Chelsey Ortman, Rohini Coorg, Irfan Ali, Dave Clarke, Gloria Diaz‐Medina, Kimberly Houck, Akshat Katyayan, Laura Masters, Deepankar Mohanty, Anuranjita Nayak, Michael Quach, Vijay M. Ravindra, James J. Riviello, Sonali Sen, Elaine Seto, Danielle Takacs, Cristina Trandafir, John T. Freiling, Karen Evankovich, Yingchao Yuan, Kalman A. Katlowitz, Daniel Curry, Howard L. Weiner, Anne Anderson   +23 more
wiley   +1 more source

Salivary and Serum Cytokine Concentrations in Kidney Transplantation: A Prospective Study

Oral Diseases, EarlyView.
ABSTRACT Background Kidney transplant recipients (KTRs) experience immune modulation, which may lead to graft rejection and other adverse outcomes. Although serum cytokines are well‐established systemic immune markers, the role of salivary biomarkers has never been reported in the literature.
Luciano Miziara, Marcio Augusto de Oliveira, Debora Macedo, Ligia Pierrotti, Fabiana Agena, Elias David‐Neto, Aluísio Cotrim Segurado, Rodrigo Zerbinati, Marina Gallottini, Paulo Braz‐Silva, Fabiana Martins   +10 more
wiley   +1 more source

Data from RAD001 (Everolimus) Delays Tumor Onset and Progression in a Transgenic Mouse Model of Ovarian Cancer

, 2023
Seiji Mabuchi, Deborah A. Altomare, Denise C. Connolly, Andres J. Klein–Szanto, Samuel Litwin, Matthew K. Hoelzle, Harvey H. Hensley, Thomas C. Hamilton, Joseph R. Testa   +8 more
openalex   +1 more source