Results 261 to 270 of about 4,993,323 (339)

Investigating the knowledge attitude and practice of evidence based medicine education in Sudanese medical students: a cross sectional study. [PDF]

BMC Med Educ
Amin MHJ, Awad MH, Mohamed Ginawi ES, Mohammed ASK, Noureldaiem Ibrahim EHE, Yassen OYM, Elomeiri LESMA, Hakim Hussain AHMA, Eltahir TA, Mohmmed FSAA, Wedatalla RAE, Awad KH, Mahgoub RKE, Karar AMA, Saeed AYM, Mohamed AEA, Mohamed Ginawi RS, Sidar FMK, Saifalsorori RRA, Osman OIA, Nouri MAI, Mohamed MAA, Ibrahim NBM, Mohamed MMM, Mohamed AEAB, MohamedAhmed FMA, Hassan MRM, Mohamed SAA, Bashar Hadi HE, Gandour HMNG, Ahmed NAF, Ahmed NME, Osman MMAA, Elhadi SEI.   +33 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Assessment of knowledge, attitudes, practices, and self-efficacy toward evidence-based medicine among resident physicians: a cross-sectional study from Qatar. [PDF]

Front Med (Lausanne)
Mohammed Ahmed W, Aabdien M, Mohamed A, Bougmiza MI.   +3 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Evidence-Based Medicine: <i>Knowledge, attitudes and practices among senior medical students and interns in Oman</i>. [PDF]

Sultan Qaboos Univ Med J
Al-Hadhrami RS, Al-Shaqsi AN, Thuhli ZMA, Sabbari MYA.   +3 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

GLP-1 receptor agonist for weight loss and fertility: Social media and online perception versus evidence-based medicine. [PDF]

PLoS One
Merhi Z, Karekar M, Mouanness M.
europepmc   +1 more source

Contextualizing science in the aftermath of the evidence-based medicine era: on the need for person-centered healthcare

, 2013
Andrew Miles, Jonathan Asbridge
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The impact of evidence-based medicine curricula on information literacy among clinical medical undergraduates and postgraduates in China. [PDF]

BMC Med Educ
Wang C, Yao Y, Chen Y, Chen J.
europepmc   +1 more source