Results 51 to 60 of about 4,688,320 (340)

Acupuncture for ulcerative colitis: a systematic review and meta-analysis of randomized clinical trials

BMC Complementary Medicine and Therapies, 2020
Background Ulcerative colitis, characterized by diarrhea, bloody stools and abdominal pain, is a chronic, idiopathic inflammatory disease of the colonic mucosa.
Xiao Wang, Nan-qi Zhao, Yu-xin Sun, Xue Bai, Jiang-tao Si, Jian-ping Liu, Zhao-lan Liu   +6 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

A systematic review of high quality randomized controlled trials investigating motor skill programmes for children with developmental coordination disorder. [PDF]

, 2017
To identify effective motor training interventions for children with developmental coordination disorder from research graded as high quality (using objective criteria) for the purpose of informing evidence-based clinical practice.We followed the ...
Bruininks R, Centre for Evidence-Based Physiotherapy, Centre for Reviews and Dissemination, Chia CLC, Coe R, Elizabeth Andrews, Henderson S, Henderson SE, Hillier S, Liam JB Hill, Mark Mon-Williams, Nick Preston, Oxford Centre for Evidence-based Medicine Levels of Evidence Working Group, Polatajko H, Sara M Ahern, Sara Magallón, Silkwood-Sherer D   +16 more
core   +2 more sources

Design and statistical analysis reporting among interrupted time series studies in drug utilization research: a cross-sectional survey

BMC Medical Research Methodology
Introduction Interrupted time series (ITS) design is a commonly used method for evaluating large-scale interventions in clinical practice or public health. However, improperly using this method can lead to biased results.
Yuanjin Zhang, Yan Ren, Yunxiang Huang, Minghong Yao, Yulong Jia, Yuning Wang, Fan Mei, Kang Zou, Jing Tan, Xin Sun   +9 more
doaj   +1 more source

Neutrophil-to-albumin ratio as a predictor of mortality in patients with intracerebral hemorrhage: a multicenter retrospective cohort study

BMC Neurology
Background Intracerebral hemorrhage (ICH) is associated with a poor prognosis. The association between the neutrophil-to-albumin ratio (NAR) with mortality in patients with ICH remains underexplored.
Jun Wan, Sen Zhang, Xiang Yuan, Yuyang Liu, Xin Cheng, Hao Liu, Fengrui Yang, Yinquan Ai, Xiaohong Luo, Yuting Zhong, Shiqiao Liu, Yu Zhang   +11 more
doaj   +1 more source

Oral and injectable Marsdenia tenacissima extract (MTE) as adjuvant therapy to chemotherapy for gastric cancer: a systematic review

BMC Complementary and Alternative Medicine, 2019
Background Marsdenia tenacissima extract (MTE) is a phytochemical widely used as complementary therapy in cancer care. This systematic review was conducted to investigate the anticancer and detoxification effects of MTE, as an adjuvant therapy to ...
Xu Zhou, Meilu Liu, Qing Ren, Weifeng Zhu, Yang Wang, Haochen Chen, Jianrong Chen   +6 more
doaj   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Quality healthcare, evidence-based medicine and translational research [PDF]

, 2011
Advances in medical care ensure that with the passage of time we are increasingly able to effectively tackle diverse medical problems. These advances, however, do come at a cost and the benefits derived need to be assessed on a regular basis.
Vassallo, Josanne
core  

Secular trends of morbidity and mortality of prostate, bladder, and kidney cancers in China, 1990 to 2019 and their predictions to 2030

BMC Cancer, 2022
Background Prostate, bladder and kidney cancers are common age-related genitourinary cancers. China's population is aging at an increasing rate, so predicting the morbidity and mortality of prostate, bladder, and kidney cancer in China is of great ...
Qiao Huang, Hao Zi, Lisha Luo, Xuhui Li, Cong Zhu, Xiantao Zeng   +5 more
doaj   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source