Results 71 to 80 of about 2,390,694 (316)

Natalizumab in patients with multiple sclerosis in Colombia: a case series

Acta Neurológica Colombiana, 2020
INTRODUCTION: Natalizumab is a humanized monoclonal antibody prescribed in the treatment of multiple sclerosis, the most prevalent chronic and inflammatory disease of the central nervous system (CNS). NEDA (no evidence of disease activity) status is the
Juan Raúl García Bonitto, Diana González-Bravo, Laura Prieto-Pinto, Laura van der Werf, Camilo Castañeda-Cardona   +4 more
doaj   +1 more source

Secular trends of morbidity and mortality of prostate, bladder, and kidney cancers in China, 1990 to 2019 and their predictions to 2030

BMC Cancer, 2022
Background Prostate, bladder and kidney cancers are common age-related genitourinary cancers. China's population is aging at an increasing rate, so predicting the morbidity and mortality of prostate, bladder, and kidney cancer in China is of great ...
Qiao Huang, Hao Zi, Lisha Luo, Xuhui Li, Cong Zhu, Xiantao Zeng   +5 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Evidence for the medicinal value of Squama Manitis (pangolin scale): A systematic review

Integrative Medicine Research, 2021
Background: Squama Manitis (pangolin scale) has been used in traditional Chinese medicine for thousands of years. However, its efficacy has not been systematically reviewed. This review aims to fill the gap.
Xinyao Jin, Hui Zi Chua, Keyi Wang, Nan Li, Wenke Zheng, Wentai Pang, Fengwen Yang, Bo Pang, Mingyan Zhang, Junhua Zhang   +9 more
doaj  

Global, regional, and national trends of syphilis from 1990 to 2019: the 2019 global burden of disease study

BMC Public Health, 2023
Background Syphilis is a sexually transmitted disease caused by Treponema pallidum, and the infection source is syphilis patients. This study aimed to estimate the incidence, mortality rate, and disability-adjusted life years (DALYs) of syphilis to ...
Yu-Ting Tao, Teng-Yu Gao, Hao-Yang Li, Yu-Tong Ma, Hui-Jun Li, Chen-Yang Xian-Yu, Nian-Jia Deng, Chao Zhang   +7 more
doaj   +1 more source

Feedback Medicine: Control Systems Concepts in Personalised, Predictive Medicine and Combinatorial Intervention [PDF]

arXiv, 2006
In its broadest definition, systems biology is the application of a `systems' way of thinking about and doing cell biology. By implication, this also invites us to consider a systems approach in the context of medicine and the treatment of disease. In particular, the idea that systems biology can form the basis of a personalised, predictive medicine ...
arxiv  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Analysis of Bacteriostatic Effect of Chinese Herbal Medicine Against E.coli [PDF]

arXiv, 2017
To analyze the bacteriostatic effect of Chinese traditional herbal medicines on E. coli, total 35 different preparations (decoction, volatile oil and distillate) of Chinese traditional herbal medicines were tested using plate culture method. The results showed that 18 preparations of traditional Chinese herbal medicines have different inhibition effect
arxiv  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Research Collaboration and Outcome Measures of Interventional Clinical Trial Protocols for COVID-19 in China

Frontiers in Public Health, 2020
Background: Research collaboration of registered clinical trials for Coronavirus Disease 2019 (COVID-19) remains unclear. This study aimed to analyze research collaboration and distribution of outcome measures in registered interventional clinical trials
Ya Gao, Kelu Yang, Ming Liu, Yamin Chen, Shuzhen Shi, Fengwen Yang, Jinhui Tian, Jinhui Tian, Jinhui Tian   +8 more
doaj   +1 more source