Results 71 to 80 of about 4,993,323 (339)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Research Collaboration and Outcome Measures of Interventional Clinical Trial Protocols for COVID-19 in China

Frontiers in Public Health, 2020
Background: Research collaboration of registered clinical trials for Coronavirus Disease 2019 (COVID-19) remains unclear. This study aimed to analyze research collaboration and distribution of outcome measures in registered interventional clinical trials
Ya Gao, Kelu Yang, Ming Liu, Yamin Chen, Shuzhen Shi, Fengwen Yang, Jinhui Tian, Jinhui Tian, Jinhui Tian   +8 more
doaj   +1 more source

Evidence-Based Design: Theoretical and Practical Reflections of an Emerging Approach in Office Architecture [PDF]

, 2009
Evidence-based design is a practice that has emerged only relatively recently, inspired by a growing popularity of evidence-based approaches in other professions such as medicine.
Budgen, Andrew, Lonsdale, Nathan, Penn, Alan, Sailer, Kerstin, Turner, Alasdair   +4 more
core  

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Evidence-based occupational health and safety interventions: a comprehensive overview of reviews

BMJ Open, 2019
Objectives Occupational injuries and diseases are a huge public health problem and cause extensive suffering and loss of productivity. Nevertheless, many occupational health and safety (OHS) guidelines are still not based on the best available evidence ...
Birgit Teufer, Irma Klerings, Lisa Affengruber, Agnes Ebenberger, Christina Kien, Monika Szelag, Ludwig Grillich, Ursula Griebler   +7 more
doaj   +1 more source

"Knowledge-based (personalized) medicine” instead of "evidence-based (cohort) medicine” [PDF]

, 2017
No abstract ...
Hunziker, Patrick
core  

Does the Removal of Textbook Reading from Emergency Medicine Resident Education Negatively Affect In-Service Scores? [PDF]

, 2020
Introduction: In-service exam scores are used by residency programs as a marker for progress and success on board exams. Conference curriculum helps residents prepare for these exams.
Bove, Joseph, Hochman, Steven, Ju, Christine   +2 more
core  

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

How fragile the positive results of Chinese herbal medicine randomized controlled trials on irritable bowel syndrome are?

BMC Complementary Medicine and Therapies
Objective The fragility index (FI), which is the minimum number of changes in status from “event” to “non-event” resulting in a loss of statistical significance, serves as a significant supplementary indicator for clinical physicians in interpreting ...
Minjing Luo, Jinghan Huang, Yingqiao Wang, Yilin Li, Zhihan Liu, Meijun Liu, Yunci Tao, Rui Cao, Qianyun Chai, Jianping Liu, Yutong Fei   +10 more
doaj   +1 more source