Results 71 to 80 of about 6,906,802 (378)

Quality healthcare, evidence-based medicine and translational research [PDF]

open access: yes, 2011
Advances in medical care ensure that with the passage of time we are increasingly able to effectively tackle diverse medical problems. These advances, however, do come at a cost and the benefits derived need to be assessed on a regular basis.
Vassallo, Josanne
core  

Evidence based medicine [PDF]

open access: yesBMJ, 1995
Busy doctors have never had time to read all the journals in their disciplines. There are, for example, about 20 clinical journals in adult internal medicine that report studies of direct importance to clinical practice, and in 1992 these journals included over 6000 articles with abstracts: to keep up the dedicated doctor would need to read about 17 ...
F, Davidoff   +3 more
openaire   +2 more sources

Point-of-care ultrasound (POCUS): unnecessary gadgetry or evidence-based medicine?

open access: yesClinical medicine (London), 2018
Over the last decade there has been increasing interest and enthusiasm in point-of-care ultrasound (POCUS) as an aide to traditional examination techniques in assessing acutely unwell adult patients.
N. Smallwood, M. Dachsel
semanticscholar   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Design and statistical analysis reporting among interrupted time series studies in drug utilization research: a cross-sectional survey

open access: yesBMC Medical Research Methodology
Introduction Interrupted time series (ITS) design is a commonly used method for evaluating large-scale interventions in clinical practice or public health. However, improperly using this method can lead to biased results.
Yuanjin Zhang   +9 more
doaj   +1 more source

Evidence-based medicine and precision medicine: Complementary approaches to clinical decision-making

open access: yesPrecision Clinical Medicine, 2018
Evidence-based medicine is widely promoted for decision-making in health care and is associated with improved patient outcomes. Critics have suggested that evidence-based medicine focuses primarily on groups of patients rather than individuals, but often
Ngai Chow, L. Gallo, J. Busse
semanticscholar   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

Neutrophil-to-albumin ratio as a predictor of mortality in patients with intracerebral hemorrhage: a multicenter retrospective cohort study

open access: yesBMC Neurology
Background Intracerebral hemorrhage (ICH) is associated with a poor prognosis. The association between the neutrophil-to-albumin ratio (NAR) with mortality in patients with ICH remains underexplored.
Jun Wan   +11 more
doaj   +1 more source

Secular trends of morbidity and mortality of prostate, bladder, and kidney cancers in China, 1990 to 2019 and their predictions to 2030

open access: yesBMC Cancer, 2022
Background Prostate, bladder and kidney cancers are common age-related genitourinary cancers. China's population is aging at an increasing rate, so predicting the morbidity and mortality of prostate, bladder, and kidney cancer in China is of great ...
Qiao Huang   +5 more
doaj   +1 more source

Efficacy and safety of herbal medicine (Lianhuaqingwen) for treating COVID-19: A systematic review and meta-analysis

open access: yesIntegrative Medicine Research, 2021
Background: Lianhuaqingwen (LH) has been proven effective for influenza. However, the promotion of LH for the treatment of patients with COVID-19 remains controversial.
Ming Liu   +6 more
doaj   +1 more source

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