Results 61 to 70 of about 5,186,936 (309)

Role of professional networks on social media in addressing clinical questions at general practice: a cross-sectional study of general practitioners in Australia and New Zealand

BMC Family Practice, 2019
Background Clinicians frequently have questions about patient care. However, for more than half of the generated questions, answers are never pursued, and if they are, often not answered satisfactorily.
Loai Albarqouni, Tammy Hoffmann, Katrina McLean, Karen Price, Paul Glasziou   +4 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Changing Peripheral Intravenous Catheter When Clinically Indicated: First Evidence-Based Practice Project in Makkah, Saudi Arabia

Evidence-Based Nursing Research
Context: In the past, it was advised to replace peripheral intravenous catheters every 24 to 96 hours (about four days). Regular catheter removal under a time-based method was utilized for a considerable amount of time to prevent consequences.
Faisal Alasmari, Ebtisam Alhihi, Mohammed Paredath, Sarah Alqurashi   +3 more
doaj   +1 more source

The effect of culinary interventions (cooking classes) on dietary intake and behavioral change: a systematic review and evidence map

BMC Nutrition, 2019
Background Culinary interventions (cooking classes) have been used to improve the quality of dietary intake and change behavior. The aim of this systematic review is to investigate the effects of culinary interventions on dietary intake and behavioral ...
Bashar Hasan, Warren G. Thompson, Jehad Almasri, Zhen Wang, Sumaya Lakis, Larry J. Prokop, Donald D. Hensrud, Kristen S. Frie, Mary J. Wirtz, Angela L. Murad, Jason S. Ewoldt, M. Hassan Murad   +11 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Diabetes drugs for nonalcoholic fatty liver disease: a systematic review

Systematic Reviews, 2019
Background Fatty liver is associated with obesity, type 2 diabetes, hyperlipidemia, hypertension, and metabolic syndrome. While there are no approved drugs for the treatment of nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis ...
Ian Blazina, Shelley Selph
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An analysis of reporting quality of prospective studies examining community antibiotic use and resistance

Trials, 2018
Background Antibiotic resistance is a global problem, but the relationship between antibiotic use and resistance development and decay is not well understood.
Mina Bakhit, Chris Del Mar, Anna Mae Scott, Tammy Hoffmann   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Concordance between humans and GPT-4 in appraising the methodological quality of case reports and case series using the Murad tool

BMC Medical Research Methodology
Background Assessing the methodological quality of case reports and case series is challenging due to human judgment variability and time constraints.
Zin Tarakji, Adel Kanaan, Samer Saadi, Mohammed Firwana, Adel Kabbara Allababidi, Mohamed F. Abusalih, Rami Basmaci, Tamim I. Rajjo, Zhen Wang, M. Hassan Murad, Bashar Hasan   +10 more
doaj   +1 more source