Results 71 to 80 of about 5,186,936 (309)

Educational interventions to improve people’s understanding of key concepts in assessing the effects of health interventions: a systematic review

Systematic Reviews, 2018
Background Health information is readily accessible but is of variable quality. General knowledge about how to assess whether claims about health interventions are trustworthy is not common, so people’s health decisions can be ill-informed, unnecessarily
Leila Cusack, Chris B. Del Mar, Iain Chalmers, Elizabeth Gibson, Tammy C. Hoffmann   +4 more
doaj   +1 more source

Evidence based practice readiness: A concept analysis

Journal of Nursing Management, 2018
AIM To analyse and define the concept "evidence based practice readiness" in nurses. BACKGROUND Evidence based practice readiness is a term commonly used in health literature, but without a clear understanding of what readiness means.
Jessica D Schaefer, J. Welton
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Knowledge, Attitudes, and Practice about Evidence-Based Practice: A Jordanian Study

, 2017
Background: Evidence-based practice has become a worldwide concern for healthcare staff and administrators as well as researchers. Evidence-based practice has been considered as critical element to improve quality of health services and achieving ...
M. Aburuz, Haneen M. Abu Hayeah, Ghadeer Al-Dweik, H. Al-Akash   +3 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Shared decision making and antibiotic benefit-harm conversations: an observational study of consultations between general practitioners and patients with acute respiratory infections

BMC Family Practice, 2018
Background Little research has examined whether shared decision making (SDM) occurs in consultations for acute respiratory infections (ARIs), including what, and how, antibiotic benefits and harms are discussed.
Mina Bakhit, Chris Del Mar, Elizabeth Gibson, Tammy Hoffmann   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Financial Toxicity of Partial Versus Whole Breast Irradiation: A Systematic Review

Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Objective: To determine if accelerated partial breast irradiation (APBI) is associated with less financial toxicity (financial difficulties that patients experience due to treatment, such as out-of-pocket costs, transportation costs, and time away from ...
Taema Brinjikji, MD, Kimberly S. Corbin, MD, Zhen Wang, PhD, M. Hassan Murad, MD, Dean A. Shumway, MD   +4 more
doaj   +1 more source

The Contribution of Individual Exercise Training Components to Clinical Outcomes in Randomised Controlled Trials of Cardiac Rehabilitation: A Systematic Review and Meta-regression

Sports Medicine - Open, 2017
Background While the clinical benefits of exercise-based cardiac rehabilitation are well established, there is extensive variation in the interventions used within these trials.
Bridget Abell, Paul Glasziou, Tammy Hoffmann   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source