Results 131 to 140 of about 10,098,806 (296)
When simultaneously reasoning with evidences about several different events it is necessary to separate the evidence according to event. These events should then be handled independently. However, when propositions of evidences are weakly specified in the sense that it may not be certain to which event they are referring, this may not be directly ...
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The protocol for a subject-wide evidence synthesis of the effects of conservation interventions on terrestrial and freshwater ...
Conservation Evidence
core +1 more source
Targeted monitoring of analgesia, sedation and delirium, as well as their appropriate management in critically ill patients is a standard of care in intensive care medicine. With the undisputed advantages of goal-oriented therapy established, there was a
Kleinschmidt, Stefan +41 more
doaj
The paper discusses semantic and pragmatic relations among three concepts and terms: certainty, truth and evidence (obviousness), and provides prolegomena for a possible epistemological theory explaining how these epistemic values are interconnected ...
Jan Hartman
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Evidence Matters (October 2016)
Newsletter of the Center for Evidence-Based Practices at Case Western Reserve Universityhttps://commons.case.edu/evidence-matters/1005/thumbnail ...
Center for Evidence-Based Practices
core
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Draft Convention on Electronic Evidence
The Draft Convention is the first treaty dealing with the status of electronic evidence, covering civil and criminal proceedings; the investigation and examination of electronic evidence, and general provisions regarding the recognition and admissibility
Electronic Evidence, Draft Convention on:
core
International experience of using expert opinions in criminal proceedings
The article is devoted to the important issue of international standards integration into the national system of forensic examination. The influence of international legal norms on the regulation of expert activity in Ukraine is analysed and the ...
O. P. Makarova
doaj +1 more source

