Results 71 to 80 of about 6,616,225 (247)

The value of uncertainty: the Zika and Microcefalia link

open access: yesJournal of Evidence-Based Healthcare, 2019
Scientific paradigm violations are common in the medical literature. This article aims to describe the principles that should guide scientific thinking, such as the philosophy of skepticism, the consideration of multiple hypothesis, epidemiological ...
Denise Silva Matias   +7 more
doaj   +1 more source

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia   +6 more
wiley   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology
Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive
Amin Mehrabian   +9 more
doaj   +1 more source

Comparative effectiveness of beta-interferons and glatiramer acetate for relapsing-remitting multiple sclerosis: systematic review and network meta-analysis of trials including recommended dosages

open access: yesBMC Neurology, 2018
Background We systematically reviewed the comparative effectiveness of injectable beta-interferons (IFN-β) and glatiramer acetate (GA) on annualised relapse rate (ARR), progression and discontinuation due to adverse events (AEs) in RRMS, using evidence ...
G. J. Melendez-Torres   +9 more
doaj   +1 more source

The Relationship Between Physical Activity and Left Ventricular Remodeling in Childhood Cancer Survivors Treated With Anthracyclines: A Cross‐Sectional Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Anthracycline‐related cardiac remodeling precedes heart failure in childhood cancer survivors. The objectives of this study were to determine the relationships between patient‐specific factors, moderate‐to‐vigorous physical activity (MVPA), and cardiac remodeling.
Hari K. Narayan   +15 more
wiley   +1 more source

Pulmonary Function Decline in Alpha-1 Antitrypsin Deficiency: A Systematic Review and Meta-Analysis

open access: yesInternational Journal of COPD
Alice M Turner,1 Priscilla Wittkopf,2 Caroline von Wilamowitz-Moellendorff,2 Kyle Fahrbach,3 Mariana Farraia,4 May Hagiwara,5 Ed G Marins,5 Anne E Wyman,5 Lisi Wang,5 Suna Park5 1School of Health Sciences, University of Birmingham, Birmingham, UK ...
Turner AM   +9 more
doaj  

ASSIST: Refinement of a Benefits Navigator Intervention Among Low‐Income Pediatric Oncology Families

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Children with cancer living in poverty experience worse survival and quality of life. Interventions connecting low‐income families to benefits (e.g., Supplemental Nutrition Assistance Program [SNAP] improve health outcomes; yet nearly 50% of SNAP‐eligible pediatric oncology families are unenrolled.
Puja J. Umaretiya   +11 more
wiley   +1 more source

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