Results 171 to 180 of about 9,419,823 (304)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Toward Evidence Synthesis of Adverse Events in Imbalanced Time-to-Event Data. [PDF]

J Evid Based Med
Peng Z, Jiang J, Lin L, Furuya-Kanamori L, Li S, Loke Y, Chu H, Vohra S, Xu C.   +8 more
europepmc   +1 more source

What national and subnational interventions and policies based on Mediterranean and Nordic diets are recommended or implemented in the WHO European Region, and is there evidence of effectiveness in reducing noncommunicable diseases?

, 2018
ix + 58 p.Studies have established the health promoting properties of two European diets: the Mediterranean diet and the Nordic diet. However, guidance is lacking on how to effectively translate the health benefits of these diets into specific ...
Breda, João, Wickramasinghe, Kremlin, Renzella, Jessica, Townsend, Nick, Rayner, Mike, Roberts, Nia, Jewell, Jo   +6 more
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Men's Experiences and Decision-Making in Erectile Dysfunction Treatment: A Qualitative Evidence Synthesis. [PDF]

Cureus
Ullah A, Hussain AK, Chaudhry T.
europepmc   +1 more source

Synthesis of UK evidence based recommendations for adult obesity prevention and treatment for service improvement and implementation

, 2015
This is a synthesis of UK evidence-based recommendations for adult obesity prevention and treatment services, produced by the Why Weight East Midlands AHSN team. It is intended as a ‘user-friendly’ summary of existing multiple sets of, often overlapping,
Ward, Derek, Kai, Joe, Bird, Lydia, Cross-Bardell, Laura   +3 more
core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Expanding the Scope of Prompt Engineering Training for Information Specialists in Evidence Synthesis. [PDF]

Campbell Syst Rev
Trushna T, Yadav V, Mandal UK, Sabde YD.
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source