Results 101 to 110 of about 40,212 (295)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Two Uummarmiutun modals – including a brief comparison with Utkuhikšalingmiutut cognates [PDF]

open access: yes, 2017
The paper is concerned with the meaning of two modal postbases in Uummarmiutun, hungnaq ‘probably’ and ȓukȓau ‘should’. Uummarmiutun is an Inuktut dialect spoken in the Western Arctic.
Berthelin, Signe Rix
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

"Omen" partikularen erabilera eta gaztelaniazko ordainak: Anjel Lertxundiren kasua / The use of the "omen" particle and its equivalents in Spanish: The case of Anjel Lertxundi

open access: yesAnuario del Seminario de Filología Vasca "Julio de Urquijo", 2018
The Basque evidential particle omen is very interesting for bascologists (Basque linguists) and Basque translators. For linguists, due to the fact that the two neighboring languages (Spanish and French) lack a similar particle, and for translators ...
Karlos Cid Abasolo
doaj  

Evidential multi-model CNN integration for visual fault detection in solar panels

open access: yesNext Energy
This study proposes an evidential fusion framework for classifying visual defects in solar panels using convolutional neural networks (CNNs) and Dempster-Shafer theory (DST). Three pretrained CNN models: ResNet50, MobileNetV2, and EfficientNetB0 are fine-
Nadjia Khatir, Safia Nait-Bahloul
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The use of the "omen" particle and its equivalents in Spanish: The case of Anjel Lertxundi

open access: yesAnuario del Seminario de Filología Vasca "Julio de Urquijo", 2018
The Basque evidential particle omen is very interesting for bascologists (Basque linguists) and Basque translators. For linguists, due to the fact that the two neighboring languages (Spanish and French) lack a similar particle, and for translators ...
Karlos Cid Abasolo
doaj  

Nomination and Argumentation Strategies in Oratory Discourse: The Case of an English Sermon

open access: yesSAGE Open, 2017
Inspired by critical discourse analysis and regarding language as a social medium whereby individuals, social groups, and institutions tend to express their beliefs and values, this study seeks to explore the persuasion and discourse strategies utilized ...
Sara Mansouri   +3 more
doaj   +1 more source

Probabilistic expert systems for handling artifacts in complex DNA mixtures [PDF]

open access: yes, 2009
This paper presents a coherent probabilistic framework for taking account of allelic dropout, stutter bands and silent alleles when interpreting STR DNA profiles from a mixture sample using peak size information arising from a PCR analysis.
Cowell, R.   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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