Results 91 to 100 of about 2,635 (296)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Intersubjective strategies in deontic modality: evidential functions of Spanish deber ‘must’
Kalbotyra, 2017 The principal aim of this study is to examine the Spanish modal verb deber ‘must’ in its deontic readings, relating it to the notions of evidentiality and intersubjectivity.
Miriam Thegel
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Kalbotyra, 2017 Most research on evidentiality has focused on classifying evidential systems synchronically; meanwhile, diachronic studies on evidentiality seem to have focused on the development of specific items into evidential markers with little regard to discourse ...
Richard J. Whitt
doaj +1 more source
Evidentiality in Formosan Languages
, 2018 This chapter investigates evidentiality in Formosan languages. Five Formosan languages—Bunun, Paiwan, Kanakanavu, Saaroa, and Tsou—are discussed. Evidentiality in these languages is a grammatical category in its own right, and not a subcategory of ...
Chia-Jung Pan
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A Modification to Evidential Probability [PDF]
, 1991 Selecting the right reference class and the right interval when faced with conflicting candidates and no possibility of establishing subset style dominance has been a problem for Kyburg's Evidential Probability system. Various methods have been proposed by Loui and Kyburg to solve this problem in a way that is both intuitively appealing and justifiable
Bülent Murtezaoglu, Henry E. Kyburg Jr.
openaire +3 more sources
, 2018 Evidentiality and stereotyping are two highly productive concepts that have recently generated interesting, and in the case of stereotypes, often politically intense, research agendas. This paper initially outlines how some of this productivity relies on
Michael Wood
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source