Results 101 to 110 of about 3,788 (240)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A modular approach to evidentiality [PDF]
, 2018 Evidentiality is a well-established morphosyntactic category that has also received a lot of attention in the semantics literature over the last 15+ years.
Toivonen, I, Asudeh, A, Asudeh, Arshia
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Two Classes of Intensifiers in Mandarin Chinese: From Subjectivity to Evidentiality
LogicsThis article investigates two distinct classes of intensifiers in Mandarin Chinese, ordinary intensifiers (Class I) and subjective intensifiers (Class II).
Jiayi Zhou
doaj +1 more source
, 2018 Evidentiality and stereotyping are two highly productive concepts that have recently generated interesting, and in the case of stereotypes, often politically intense, research agendas. This paper initially outlines how some of this productivity relies on
Michael Wood
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Evidentiality in Bodic Languages
, 2018 The Bodic group of Tibeto-Burman languages infamously code a wide range of epistemological categories, including evidentiality (source of knowledge) and perhaps more contentiously mirativity (expectations of knowledge), and egophoricity (access to ...
Gwendoyn Hyslop
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The present paper deals with the definition of evidentiality and the position of mirativity and egophoricity in the category of evidentiality, based on the analysis of the function of some elements in Sibe (Manchu-Tungusic).
Kogura, Norikazu, 児倉, 徳和
core +1 more source