Results 71 to 80 of about 672,774 (331)
Aspetto ed evidenzialità in kazako
RiCognizioni, 2015 The purpose of this paper is to examine evidentiality in reference to Central Asian context, in particular to Kazakh language. The first section proposes a problematic definition of evidentiality, firstly introducing the most common theories ...
Giulia Orlando
doaj +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Intersubjective strategies in deontic modality: evidential functions of Spanish deber ‘must’
Kalbotyra, 2017 The principal aim of this study is to examine the Spanish modal verb deber ‘must’ in its deontic readings, relating it to the notions of evidentiality and intersubjectivity.
Miriam Thegel
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Kalbotyra, 2017 Most research on evidentiality has focused on classifying evidential systems synchronically; meanwhile, diachronic studies on evidentiality seem to have focused on the development of specific items into evidential markers with little regard to discourse ...
Richard J. Whitt
doaj +1 more source
, 2011 Evidentiality is a grammatical category with source of information as its primary meaning—whether the speaker saw the event happen, did not see it but heard it, made an inference based on general knowledge or visual traces, or was told about it. Languages may distinguish firsthand and nonfirsthand information or have a special marker just for reported ...
openaire +2 more sources
Analysis, 2020 AbstractA considerable literature has grown up around the claim of Uniqueness, according to which evidence rationally determines belief. It is opposed to Permissivism, according to which evidence underdetermines belief. This paper highlights an overlooked third possibility, according to which there is no rational doxastic attitude.
openaire +2 more sources
Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source