Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Mirativity and evidentiality in Bantu
Studies in African LinguisticsThis special issue addresses how evidentiality and mirativity are expressed in various Bantu languages. Both the notions of evidentiality and mirativity remain underexamined for the Bantu languages – the following quote is quite typical: “It appears ...
Hannah Gibson, Jenneke van der Waal
doaj
Evidentiality and Determination
, 2007 This paper investigates the semantic properties of the French determiner quelque. It is shown that quelque conveys inferential evidentiality, that is, it selects interpretations in which the speaker infers the proposition conveyed by the sentence that hosts the determiner.
Jayez, Jacques, Tovena, Lucia M.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of external factors on the reactivation of the heritage language of Turkish-German returnees. [PDF]
Front Psychol, 2023 Antonova-Unlu E, Bayram F.
europepmc +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
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Evidentiality in South Estonian [PDF]
Linguistica Uralica, 2022 Helle Metslang, Karl Pajusalu
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Un tal Ernestico/a certain Ernestico: On the structure of proper names
Glossa, 2019 Proper names are usually assumed to be definite. In this paper we question this assumption by analyzing the Spanish construction un tal ‘X’ ‘a certain ‘X’’.
José Camacho
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Does evidentiality support source monitoring and false belief understanding? A cross-linguistic study with Turkish- and English-speaking children. [PDF]
Child Dev, 2023 Kandemirci B +3 more
europepmc +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
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