Results 91 to 100 of about 790,565 (357)

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen   +4 more
wiley   +1 more source

“See No Evil”

open access: yesJACC: Cardiovascular Imaging, 2016
“In the Western world both the proverb and the image are often used to refer to a lack of moral responsibility on the part of people who refuse to acknowledge impropriety, looking the other way or feigning ignorance.”—Wikipedia [(1)][1] Consider the following scenario: a 40-year-old ...
openaire   +2 more sources

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Duchowy charakter zła: wokół myśli Fiodora Dostojewskiego

open access: yesHoryzonty Wychowania, 2017
The author of the article, founding on the works of Fyodor Dostojewski, contemplates the nature of evil. He puts forward a thesis in which Dostojewski still presents it in spiritual categories.Forthesakeofexplanationheusestwoontologicalrealities:ofGod ...
Aleksander Posacki
doaj  

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

open access: yesAdvanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying   +8 more
wiley   +1 more source

Problem zła w filozofii Józefa Tischnera

open access: yesHoryzonty Wychowania, 2017
Themostbasic,primevalaxiologicalexperienceisconnected withdiscoveringthat„thereissomethingthatshouldnotbe”.This basic experience of evil provokes man to looking for its signs.
Tadeusz Gadacz
doaj  

The Moral Argument, Existential Problems of Evil, and a Non-Existential Alternative [PDF]

open access: yes, 2019
Within this paper, it is shown that certain ethical assumptions are implicit within the claim that certain kinds of evil exist. When taken in tandem with the moral argument for the existence of God, these assumptions can be arranged in such a way as to ...
Smith, Jonathan
core   +1 more source

Ultrasound Controlled‐Release Hydrogel Promotes Diabetic Wound Healing via Neuroimmune Modulation and Synergistic ROS Scavenging

open access: yesAdvanced Science, EarlyView.
This study presents an ultrasound‐responsive hydrogel (MCF@CA) that co‐delivers a neuropeptide (CGRP) and a ROS‐scavenging manganese porphyrin to diabetic wounds. The system restores neuro‐immune communication, reprograms macrophages toward an anti‐inflammatory phenotype, and clears excess ROS, thereby accelerating wound closure and promoting mature ...
Mofan Li   +9 more
wiley   +1 more source

Evil, Freedom and Heaven [PDF]

open access: yes, 2018
By far the most respected response by theists to the problem of evil is some version of the free will defense, which rests on the twin ideas that God could not create humans with free will without them committing evil acts, and that freedom is of such ...
Cushing, Simon
core  

Interview with Rev. Fr. Abbot Philip Anderson: We Must All Build Bridges [PDF]

open access: yes, 2018
This is an excerpt of a crucial dialogue engaged in by a Hindu and an Orthodox Roman Catholic.
Subhasis Chattopadhyay, Chatterjee
core   +2 more sources

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