Results 101 to 110 of about 135,177 (248)

Semne comportamentale ale sfârşitului vremurilor: iminența Parusiei în 2 Timotei 3:1–5

open access: yesTheoRhēma, 2015
The paper deals with the issue relating to the imminence of the Parousia based on 2 Timothy 3:1–5. It answers two questions. The first is how sure are the signs that are behavioural in nature to indicate the nearness of Jesus’ second coming?
Laurențiu Moț
doaj  

Pathologic liar of Grigorije Božović [PDF]

open access: yesBaština, 2011
Rako Kozarevac is, as per the author's thinking, unusual hero in the work of Grigorije Božović, not only due to the fact he gets out from the frames of national problems of the majority of Božović's stories, but due to the fact he is one the most complex
Ahmetagić Jasmina
doaj  

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

open access: yesAdvanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li   +6 more
wiley   +1 more source

Evil Corporations in Horror Fiction

open access: yes
Corporate malfeasance is a niche area of study in the fields of criminology and criminal law. In contrast, evil corporations are very much a staple of horror fiction, so much so that directors can establish a corporation as evil with common, shorthand ...
Crofts, P
core   +1 more source

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

open access: yesAdvanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang   +4 more
wiley   +1 more source

Participation in the Christian Doctrinal and Philosophical Tradition

open access: yesSt Andrews Encyclopaedia of Theology
‘Participation’ or ‘partaking’ has featured in Christian theology since the New Testament, describing a relation of derivation, likeness, or communion.
Davison
doaj  

The Plurality of Evil

open access: yesAnali Hrvatskog Politološkog Društva, 2012
The author discusses the political implications of the sovereignty of evil, which is the core concept introduced by Derek Edyvane is his forthcoming book Civic Virtue and the Sovereignty of Evil.
Enes Kulenović
doaj  

Intentionality, Belief, and the Logical Problem of Evil

open access: yes, 2020
The logical problem of evil is the appearance of inconsistency between the existence of God and the existence of any evil at all. A defence against the logical problem of evil is an argument that purports to show that this appearance is misleading and in
Pearce, Kenneth
core  

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

open access: yesAdvanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu   +7 more
wiley   +1 more source

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang   +11 more
wiley   +1 more source

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