Results 111 to 120 of about 771,683 (301)
Leopardi “Everything Is Evil” [PDF]
, 2019 Giacomo Leopardi, a major Italian poet of the nineteenth century, was also an expert in evil to whom Schopenhauer referred as a “spiritual brother.” Leopardi wrote: “Everything is evil.
De Toffoli, Silvia
core
Advanced Science, EarlyView.This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon +21 more
wiley +1 more source
On justifications and excuses [PDF]
, 2017 The New Evil Demon problem has been hotly debated since the case was introduced in the early 1980’s (e.g. Lehrer and Cohen 1983; Cohen 1984), and there seems to be recent increased interest in the topic.
Madison, B. J. C.
core
Advanced Science, EarlyView.Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong +8 more
wiley +1 more source
The Moral Argument, Existential Problems of Evil, and a Non-Existential Alternative [PDF]
, 2019 Within this paper, it is shown that certain ethical assumptions are implicit within the claim that certain kinds of evil exist. When taken in tandem with the moral argument for the existence of God, these assumptions can be arranged in such a way as to ...
Smith, Jonathan
core +1 more source
Advanced Science, EarlyView.ABSTRACT Acute liver injury (ALI), driven by diverse insults such as drug toxicity and ischemia‐reperfusion, poses a high mortality risk and lacks targeted therapies. While reactive oxygen species (ROS), neutrophil extracellular traps (NETs), and a coordinated cell death pathway PANoptosis have been implicated, their interplay as a unified pathogenic ...
Xiaopeng Cai +13 more
wiley +1 more source
Escape from Evil? Notes on Capacity, Tragedy, Coding and Non-Destructive Immortality Projects
Oñati Socio-Legal Series, 2015 Like James Hardie-Bick’s (2015) contribution this paper elaborates on the importance for socio-legal studies of Ernest Becker’s (1924-1974) work on the destructive consequences of human … all too human forms of death denial.
Ronnie Lippens
doaj
Advanced Science, EarlyView.This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou +7 more
wiley +1 more source
Advanced Technologies for Characterizing and Detecting Battery Thermal Failure: A Review
Advanced Science, EarlyView.Illustration of advanced characterization techniques to predict battery thermal failure. ABSTRACT Energy storage is essential in accelerating the global transition toward clean and sustainable energy across various sectors. Lithium‐ion batteries (LIBs) have become increasingly significant for energy storage due to their high energy density, low ...
Yongxiu Chen +5 more
wiley +1 more source
Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation
Advanced Science, EarlyView.Nanoplastics are pervasive environmental contaminants with potentially profound implications for human health. Emerging evidence suggests a possible link between nanoplastic exposure and neurodegeneration, a key driver of ageing and dementia, yet causality remains unresolved.
Yuhuan Li +5 more
wiley +1 more source