Results 121 to 130 of about 790,565 (357)
Advanced Science, EarlyView.This study demonstrates that the imbalance between osteogenic and adipogenic differentiation in senescent BMSCs, leading to excessive adipocyte accumulation, which subsequently impairs bone regeneration in aged mice. To address this pathological dysregulation, a novel energy‐supplying hydrogel system (PBR) has been developed to restore balanced ...
Zirui He +7 more
wiley +1 more source
From Ahab to “Vilain Herodes”: Biblical Models of Evil Kings in Catholic Anti-Royalist Propaganda during Charles IX (1560–1574) and Henry III (1574–1589) [PDF]
, 2023 Andrei Constantin Sălăvăstru
openalex +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
Advanced Science, EarlyView.This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Escape from Evil? Notes on Capacity, Tragedy, Coding and Non-Destructive Immortality Projects
Oñati Socio-Legal Series, 2015 Like James Hardie-Bick’s (2015) contribution this paper elaborates on the importance for socio-legal studies of Ernest Becker’s (1924-1974) work on the destructive consequences of human … all too human forms of death denial.
Ronnie Lippens
doaj
Freedom, Morality, and the Propensity to Evil [PDF]
, 2014 In Book I of the Religion within the Boundaries of Mere Reason Kant offers an explanation of freedom and moral good and evil that is different from that offered in the Groundwork for a Metaphysics of Morals.
Kahn, Samuel
core +2 more sources
Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair
Advanced Science, EarlyView.In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang +12 more
wiley +1 more source
Advanced Science, EarlyView.This work presents the first metformin‐based COFs featuring built‐in biosafety and a unique triple‐synergy mechanism. This scalable platform achieves broad‐spectrum eradication of bacteria and viruses, enabling reusable protective membranes with exceptional biocompatibility for advanced biomedical applications and personal protection.
Jia‐Yi Liu +11 more
wiley +1 more source
Advanced Science, EarlyView.Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang +11 more
wiley +1 more source
La ética como respuesta al sufrimiento inútil en Emmanuel Levinas
Franciscanum, 2012 The aim of this article is to theme the ethic matter in Levinas’ philosophy as a reply to the senseless pain. Through the analysis of pain the author reaches the infinity of the responsibility to the Other, shown in his/her face, and consequently in God.
Analía Giménez Giubbani
doaj
Advanced Science, EarlyView.Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély +5 more
wiley +1 more source