Results 51 to 60 of about 1,790,189 (297)

Somatosensory and Motor-Evoked Potentials in Spinal Surgery [PDF]

Al-Azhar International Medical Journal, 2000
Background: Spinal surgeries could be a high risk of injury to the spinal cord, spinal nerves, and or blood vessels that may result in neurological deficits, such as paralysis, muscle weakness, pain, sphincteric disturbances, and sexual dysfunction. Aim:
Mostafa Elmaghraby, Samar Hussein, Elsayed Elmor, Mahmoud Fergany   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Microglial Activation and Neurological Symptoms in the SIV Model of NeuroAIDS: Association of MHC-II and MMP-9 Expression with Behavioral Deficits and Evoked Potential Changes

Neurobiology of Disease, 1999
HIV-1 causes cognitive and motor deficits and HIV encephalitis (HIVE) in a significant proportion of AIDS patients. Neurological impairment and HIVE are thought to result from release of cytokines and other harmful substances from infected, activated ...
Nancy E.J. Berman, Joanne K. Marcario, Chi Yong, Ravi Raghavan, Leigh A.M. Raymond, Sanjay V. Joag, Opendra Narayan, Paul D. Cheney   +7 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Changes in motor-evoked potentials.

, 2013
Motor-evoked potentials (MEP in mV) for all three somatosensory tasks separately and controls ...
Lotfi B. Merabet (290677), Magdalena Sarah Volz (290668), Felipe Fregni (252313), Mariana E. Mendonca (290673), Vanessa Suarez-Contreras (290671), Fernando Santos Pinheiro (290675)   +5 more
core   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Excitatory postsynaptic potentials in rat neocortical neurons in vitro. III. Effects of a quinoxalinedione non-NMDA receptor antagonist [PDF]

, 1990
1. Intracellular microelectrodes were used to obtain recordings from neurons in layer II/III of rat frontal cortex. A bipolar electrode positioned in layer IV of the neocortex was used to evoke postsynaptic potentials.
J. J. Hablitz, Hablitz, John H., Sutor, Bernd, B. Sutor   +3 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Impaired transmission in the corticospinal tract and gait disability in spinal cord injured persons [PDF]

, 2010
Rehabilitation following spinal cord injury is likely to depend on recovery of corticospinal systems. Here we investigate whether transmission in the corticospinal tract may explain foot drop (inability to dorsiflex ankle) in persons with spinal cord ...
Willerslev-Olsen, M., Biering-Sørensen, F., Barthélemy, D., Nielsen, J.B., Knudsen, H., Conway, B.A., Lundell, Henrik   +6 more
core   +1 more source