Results 61 to 70 of about 1,578,982 (293)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Low-Frequency Local Field Potentials and Spikes in Primary Visual Cortex Convey Independent Visual Information [PDF]

, 2008
Local field potentials (LFPs) reflect subthreshold integrative processes that complement spike train measures. However, little is yet known about the differences between how LFPs and spikes encode rich naturalistic sensory stimuli.
Belitski, A., Logothetis, Nikos K., Magri, C., C. Magri, Montemurro, M.A., Logothetis, N, Panzeri, S, Logothetis, N.K., A. Belitski, Panzeri, Stefano, Murayama, Y., Gretton, A., Y. Murayama, Magri, C, Gretton, A, Murayama, Y, Montemurro, M, Murayama, Yusuke, M. A. Montemurro, N. K. Logothetis, Belitski, Andrei, Panzeri, S., Logothetis, N., Magri, Cesare, Montemurro, Marcelo A., A. Gretton, S. Panzeri, Gretton, Arthur, Belitski, A, Montemurro, M., Montemurro M. A., Murayama Y., Belitski A., Logothetis N. K., Magri C., Gretton A., Panzeri S.   +36 more
core   +1 more source

Marked attenuation of the amplitude of transcranial motor-evoked potentials after intravenous bolus administration of ketamine: a case report

Journal of Medical Case Reports, 2018
Background It is believed that ketamine does not affect motor-evoked potential amplitude, whereas various anesthetic drugs attenuate the amplitude of transcranial motor-evoked potential.
Kenta Furutani, Mari Matsuhashi, Hiroyuki Deguchi, Yusuke Mitsuma, Nobuko Ohashi, Hiroshi Baba   +5 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Intraoperative response of the pyramidal system to surgical correction of spinal deformities of various etiologies

Хирургия позвоночника, 2019
Objective. To assess the information value of comparing the results of formalizing intraoperative changes in transcranial motor evoked potentials during surgical correction of spinal deformities of various etiologies. Material and Methods.
Marat S. Saifutdinov, Sergey O. Ryabykh, Dmitry M. Savin, Polina V. Ochirova, Egor Yu. Filatov   +4 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Multichannel EEG : towards applications in clinical neurology. [PDF]

, 2008
Electroencephalogram (EEG) measures the electric activity produced by the brain with electrodes placed on the scalp. It is used for monitoring or as diagnostic tool for neurological disorders. In practice a maximum of 21 electrodes are generally used for
Wassenberg, Wilhelmina Johanna Gerarda van de, Wassenberg, Wilhelmina Johanna Gerarda van de,   +1 more
core   +16 more sources

Time-resolved influences of functional DAT1 and COMT variants on visual perception and post-processing [PDF]

, 2012
BACKGROUND: Dopamine plays an important role in orienting and the regulation of selective attention to relevant stimulus characteristics. Thus, we examined the influences of functional variants related to dopamine inactivation in the dopamine transporter
Laucht, Manfred (Prof. Dr.), Rellum Thomas, Thomas Rellum, Resch, Franz, Stephan Bender, Brandeis, Daniel, Banaschewski, Tobias, Laucht Manfred, Bender, Stephan, Rietschel, Marcella, Jennen-Steinmetz, Christine, Freitag, Christine M., Treutlein, Jens, Jens Treutlein, Rellum, Thomas, Daniel Brandeis, Brandeis Daniel, Tobias Banaschewski, Jennen-Steinmetz Christine, Christine Freitag, Bender Stephan, Banaschewski Tobias, Manfred Laucht, Freitag, Christine, Franz Resch, Rietschel Marcella, Marcella Rietschel, Resch Franz, Christine Jennen-Steinmetz, Laucht, Manfred, Treutlein Jens, Freitag Christine   +31 more
core   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source