Results 61 to 70 of about 129,435 (304)

Excitability of motor cortices as a function of emotional sounds. [PDF]

open access: yesPLoS ONE, 2013
We used transcranial magnetic stimulation (TMS) to clarify how non-verbal emotionally-characterized sounds modulate the excitability of the corticospinal motor tract (CST).
Naeem Komeilipoor   +3 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Auditory evoked potentials and vestibular evoked myogenic potentials in evaluation of brainstem lesions in multiple sclerosis [PDF]

open access: yes, 2013
OBJECTIVE: The aim of this study was to determine the roles of magnetic resonance imaging (MRI), auditory evoked potentials (AEP) and vestibular evoked myogenic potentials (VEMP) in the evaluation of brainstem involvement in multiple sclerosis (MS). -
Adamec, Ivan   +6 more
core   +1 more source

Marked attenuation of the amplitude of transcranial motor-evoked potentials after intravenous bolus administration of ketamine: a case report

open access: yesJournal of Medical Case Reports, 2018
Background It is believed that ketamine does not affect motor-evoked potential amplitude, whereas various anesthetic drugs attenuate the amplitude of transcranial motor-evoked potential.
Kenta Furutani   +5 more
doaj   +1 more source

Somatic tinnitus: clinical and neurophysiological features [PDF]

open access: yesНаука и инновации в медицине, 2019
Objectives to identify variations in the intensity of tinnitus during the certain motor maneuvers, to evaluate the clinical and neurophysiological features of modulation in patients with tinnitus.
Alfiya R. Gilaeva   +2 more
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Neurophysiological correlates of the rubber hand illusion in late evoked and alpha/beta band activity [PDF]

open access: yes, 2017
The rubber hand illusion (RHI) allows insights into how the brain resolves conflicting multisensory information regarding body position and ownership. Previous neuroimaging studies have reported a variety of neurophysiological correlates of illusory hand
Kayser, Christoph, Rao, Isa S.
core   +2 more sources

Evoked potentials as biomarkers of hereditary spastic paraplegias: A case-control study.

open access: yesPLoS ONE, 2021
IntroductionThe Hereditary Spastic Paraplegias (HSP) are a group of genetic diseases that lead to slow deterioration of locomotion. Clinical scales seem to have low sensitivity in detecting disease progression, making the search for additional biomarkers
Samanta Ferraresi Brighente   +8 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Unmasking of latent synaptic connections in the cortex of the rat, elicited by a facial nerve transection [PDF]

open access: yes, 2001
Peripheral nerve injury elicits plastic changes in the cortex, resulting in reorganization of the somatotopic representation maps. These processes begin within minutes after nerve injury, and last for weeks.
Farkas, Tamás, Toldi, József
core  

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