Results 81 to 90 of about 129,435 (304)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Command Interneurons in the Crayfish Central Nervous System [PDF]

open access: yes, 1967
The motor effects evoked by stimulation of each of eight command fibres in the circumoesophageal commissures of the crayfish are described. The fibres obtained appeared to have widespread connexions in all or most of the lower ganglia. For certain fibres
Atwood, H. L., Wiersma, C. A. G.
core  

Prismatic adaptation modulates oscillatory EEG correlates of motor preparation but not visual attention in healthy participants [PDF]

open access: yes, 2017
Prismatic adaption (PA) has been proposed as a tool to induce neural plasticity and is used to help neglect rehabilitation. It leads to a recalibration of visuo-motor coordination during pointing as well as to after-effects on a number of sensorimotor ...
Bracco, Martina   +3 more
core   +4 more sources

Reliability of Motor Evoked Potentials Induced by Transcranial Magnetic Stimulation: The Effects of Initial Motor Evoked Potentials Removal

open access: yesBasic and Clinical Neuroscience, 2017
Introduction: Transcranial magnetic stimulation (TMS) is a useful tool for assessment of corticospinal excitability (CSE) changes in both healthy individuals and patients with brain disorders. The usefulness of TMS-elicited motor evoked potentials (MEPs)
Fahimeh Hashemirad   +3 more
doaj  

Transcranial static magnetic field stimulation - new non-invasive brain stimulation tool

open access: yesJournal of Physical Fitness and Sports Medicine, 2016
Recent research has shown that the human motor cortex can be modulated by the application of static magnetic fields through the scalp. Transcranial static magnetic field stimulation (tSMS) has since received significant attention as a new non-invasive ...
Hikari Kirimoto   +2 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Large-scale changes in cortical dynamics triggered by repetitive somatosensory electrical stimulation. [PDF]

open access: yes, 2019
BackgroundRepetitive somatosensory electrical stimulation (SES) of forelimb peripheral nerves is a promising therapy; studies have shown that SES can improve motor function in stroke subjects with chronic deficits.
Burish, Mark J   +3 more
core   +1 more source

Flexible Neural Electrode Array Based-on Porous Graphene for Cortical Microstimulation and Sensing. [PDF]

open access: yes, 2016
Neural sensing and stimulation have been the backbone of neuroscience research, brain-machine interfaces and clinical neuromodulation therapies for decades.
Kuzum, Duygu   +4 more
core   +2 more sources

Magnetic Motor Evoked Potentials in Ponies

open access: yesJournal of Veterinary Internal Medicine, 1996
Magnetic stimulation of motor pathways was used to effect motor unit action potential recordings from forelimb and hindlimb muscles in unanesthetized ponies. Motor pathway conduction velocities to the forelimb and hindlimb were determined to be 53.8 ± 9.6 m/s‐1and 63.4 ± 8.3 m/s‐1, respectively.
I G, Mayhew, J R, Washbourne
openaire   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

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