A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel +2 more
wiley +1 more source
Behavioural and electrophysiological correlates of sensory attenuation in the somatosensory and auditory modality within a virtual reality setup. [PDF]
Giannini G +3 more
europepmc +1 more source
ABSTRACT Previous research highlights that wetness perception differs between hairy and glabrous skin, yet it remains unclear how hairs affect wetness perception in the same region. This study investigated the role of underarm hair on wetness perception to inform antiperspirant design.
Jade Ward +6 more
wiley +1 more source
The relationship between physical fitness and somatosensory brain responses in adolescents-a pilot study. [PDF]
Mase A +3 more
europepmc +1 more source
Therapeutic potential of spexin in diabetic neuropathy: Insights from in vitro and in vivo models
Abstract The present study investigated the therapeutic potential of spexin (SPX) on both in vitro and in vivo models of diabetic neuropathy (DN). A total of 40 male BALB/c mice were randomly allocated into four experimental groups (n = 10 per group): a normoglycaemic control, an untreated DN group and two SPX treatment groups (DN+SPX‐12.5 and DN+SPX ...
Mehmet Refik Bahar +5 more
wiley +1 more source
Diagnostic value of somatosensory evoked potentials for paroxysmal sympathetic hyperactivity: a retrospective cohort study. [PDF]
Liu L +5 more
europepmc +1 more source
Effects of baclofen and lorazepam on interhemispheric inhibition in humans
Abstract Transcallosal projections within the corpus callosum allow for the transfer of information between bilateral primary motor cortices (M1). Interhemispheric inhibition (IHI) is one approach to probe transcallosal communication using transcranial magnetic stimulation (TMS) whereby the motor evoked potential (MEP) elicited by TMS is reduced in ...
Faith C. Adams +8 more
wiley +1 more source
S2, S3, and S4 Sacral Dermatomal Evoked Potentials: Technical Parameters and Normative Values. [PDF]
Malladi P +3 more
europepmc +1 more source
We report a multifunctional tapered optical fiber integrating a conformal micro‐resistance temperature detector (µRTD) for local, real‐time thermometry during optical stimulation. The platform combines light‐delivery and temperature sensing within a minimally invasive footprint, enabling detection of sub‐degree cortical heating under representative ...
Antonio Balena +6 more
wiley +1 more source
Limited sensitivity of somatosensory evoked potentials as disease monitoring biomarkers in hereditary spastic paraplegias. [PDF]
Spengler FAM +6 more
europepmc +1 more source

