Results 211 to 220 of about 326,735 (329)

Neuromotor changes in postural control following bed rest

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prolonged bed rest (BR) (both horizontal and head‐down tilt) leads to neuromotor adaptations that impair postural control. Structural and functional changes occur in the brain, including a reduction in grey and white matter volume, alterations in functional connectivity, and shifts in cerebrospinal fluid distribution.
Ramona Ritzmann   +4 more
wiley   +1 more source

Kv4 channels improve the temporal processing of auditory neurons in the cochlear nucleus

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Kv4 channel improves temporal precision of auditory nerve‐evoked spikes in cochlear nucleus bushy neurons. Bushy neurons are specialized cells in processing information about temporal fine structure of sound critical for auditory tasks.
Chuangeng Zhang   +3 more
wiley   +1 more source

Somatostatin modulation of initial fusion pores in Ca2+‐triggered exocytosis from mouse chromaffin cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Somatostatin binds to a G‐protein‐coupled receptor to inhibit the release of catecholamine from chromaffin cells. This action has no impact on Ca2+ levels and is similar for Ca2+ entry through voltage‐gated Ca2 channels and for Ca2+ mobilization from the endoplasmic reticulum.
Jinbo Cheng, Meyer B. Jackson
wiley   +1 more source

Presynaptic quantal size enhancement counteracts post‐tetanic release depression

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sustained high‐frequency stimulation decreases the number of synaptic vesicles that fuse per action potential at the Drosophila neuromuscular junction. However, the postsynaptic response remains largely unchanged. An increased postsynaptic response to individual vesicles, likely driven by an increase in vesicle size resulting ...
Anu G. Nair   +5 more
wiley   +1 more source

Kif1a and intact microtubules maintain synaptic‐vesicle populations at ribbon synapses in zebrafish hair cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory hair cells of the inner ear and lateral‐line system exhibit strong synaptic‐vesicle enrichment at the presynapse, around specialized structures called ribbons. We find that hair cells in the zebrafish lateral‐line system rely on the kinesin motor protein Kif1a and microtubules to enrich synaptic vesicles at presynaptic ...
Sandeep David   +7 more
wiley   +1 more source

Acute introduction of monomeric or multimeric α‐synuclein induces distinct impacts on synaptic vesicle trafficking at lamprey giant synapses

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Monomeric and multimeric α‐synuclein were purified from HEK cells and delivered to lamprey reticulospinal (RS) synapses via axonal microinjection, followed by stimulation (20 Hz, 5 min). Ultrastructural analysis showed that both α‐synuclein species impaired intracellular vesicle trafficking, leading to synaptic vesicle loss and ...
Cristina Román‐Vendrell   +5 more
wiley   +1 more source

Synaptic communication within the microcircuits of pyramidal neurons and basket cells in the mouse prefrontal cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Basket cells represent critical building blocks of neuronal circuits in cortical regions by providing GABAergic innervation to the perisomatic region of their postsynaptic partners. In the mouse prelimbic cortex, the two basket cell types expressing parvalbumin or cholecystokinin/type I cannabinoid receptor receive unitary ...
Zsuzsanna Fekete   +5 more
wiley   +1 more source

Comparison of Subdural and Intracortical Recordings of Somatosensory Evoked Responses. [PDF]

open access: yesSensors (Basel)
Rettore Andreis F   +4 more
europepmc   +1 more source

Intersectin‐1 enhances calcium‐dependent replenishment of the readily releasable pool of synaptic vesicles during development

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend During development, Intersectin‐1 (Itsn1) translocates near voltage‐gated calcium channels (VGCCs) to enhance Ca2+‐dependent replenishment of readily releasable synaptic vesicles (SVs). In the presynaptic terminal, SVs undergo a cycle involving formation (step 1), docking (step 2), exocytosis (step 3), endocytosis (step 4) and ...
Yi‐Mei Yang   +13 more
wiley   +1 more source

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