Results 61 to 70 of about 55,554 (301)

Transcranial Direct Current Stimulation Improves Some Neurophysiological Parameters but not Clinical Outcomes after Severe Traumatic Brain Injury

open access: yesJournal of Integrative Neuroscience, 2023
Background: Disorders of consciousness (DOC) are one of the clinical hallmarks of severe traumatic brain injury (TBI). DOC impair patient life quality and increase the burden on their families and society.
Weiming Sun   +7 more
doaj   +1 more source

Long-term dynamics of somatosensory activity in a stroke model of distal middle cerebral artery oclussion [PDF]

open access: yes, 2015
A constant challenge in experimental stroke is the use of appropriate tests to identify signs of recovery and adverse effects linked to a particular therapy. In this study, we used a long-term longitudinal approach to examine the functional brain changes
Barios Heredero, Juan Antonio   +6 more
core   +2 more sources

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao   +7 more
wiley   +1 more source

Object-guided Spatial Attention in Touch: Holding the Same Object with Both Hands Delays Attentional Selection [PDF]

open access: yes, 2009
Previous research has shown that attention to a specific location on a uniform visual object spreads throughout the entire object. Here we demonstrate that, similar to the visual system, spatial attention in touch can be object guided.
Bettina Forster   +6 more
core   +1 more source

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

open access: yesAdvanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou   +7 more
wiley   +1 more source

EEG During Pedaling: Evidence for Cortical Control of Locomotor Tasks [PDF]

open access: yes, 2013
Objective: This study characterized the brain electrical activity during pedaling, a locomotor-like task, in humans. We postulated that phasic brain activity would be associated with active pedaling, consistent with a cortical role in locomotor tasks ...
Gourab, Krishnaj   +3 more
core   +2 more sources

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

open access: yesAdvanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng   +14 more
wiley   +1 more source

Pudendal somatosensory evoked potentials in normal women

open access: yesInternational Brazilian Journal of Urology, 2007
OBJECTIVE: Somatosensory evoked potential (SSEP) is an electrophysiological test used to evaluate sensory innervations in peripheral and central neuropathies.
Geraldo A. Cavalcanti   +6 more
doaj   +1 more source

Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output

open access: yesAdvanced Science, EarlyView.
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin   +2 more
wiley   +1 more source

Quantifying the effect of isoflurane and nitrous oxide on somatosensory-evoked potentials

open access: yesIndian Journal of Anaesthesia, 2010
Anaesthetic techniques may have a significant effect on intraoperative-evoked potentials (EP). The present study is designed to compare Propofol anaesthesia with Isoflurane (with or without nitrous oxide) during intraoperative somatosensory-evoked ...
Usha Devadoss, S Babu, V T Cherian
doaj   +1 more source

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