Results 101 to 110 of about 477,042 (311)

What associative learning in insects tells us about the evolution of learning and fixed behavior [PDF]

open access: yes, 2015
Contemporary models for the evolution of learning suggest that environmental predictability plays a critical role in whether learning is expected to evolve in a particular species, a claim originally made over 50 years ago.
Hollis, Karen L.   +3 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Autocatalysis as The Natural Philosophy Underlying Complexity and Biological Evolution [PDF]

open access: yes
The importance and different aspects of autocatalysis in evolution was analyzed. The behaviour of autocatalytic reactions mainly the Lotka-Volterra and the Schlögl equations were discussed in terms of phase change, entropy, and their oscillation ...
Gungor Gunduz
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Revisiting the Fundamental Metallicity Relation with Observation and Simulation

open access: yesThe Astrophysical Journal Letters
The gas-phase metallicity of galaxies is regulated by multiple astrophysical processes, which makes it a crucial diagnostic of galaxy formation and evolution.
Chengyu Ma   +9 more
doaj   +1 more source

Evolution of self-maintaining cellular information processing networks [PDF]

open access: yes, 2011
We examine the role of self-maintenance (collective autocatalysis) in the evolution of computational biochemical networks. In primitive proto-cells (lacking separate genetic machinery) self-maintenance is a necessary condition for the direct reproduction
McMullin, Barry, Decraene, James
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Thermodynamic evolution theorem for chemical reactions

open access: yesPhysical Review Research, 2020
The production, exchange, and balance of entropy characterize the thermodynamics of open nonequilibrium systems, ranging from chemical reactions, cells, ecological systems, and Earth-like planets to stars.
David Hochberg, Josep M. Ribó
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The chemical evolution of galaxies

open access: yes
Metals -- heavy elements synthesized during various phases of stellar evolution or during supernova explosions -- play a fundamental role in shaping galaxy evolution. In fact, their relative abundances, spatial distribution, and scaling with galactic properties reflect the constant interplay between star-formation, nucleosynthesis, and gas flows that ...
openaire   +2 more sources

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