Results 81 to 90 of about 1,651,932 (286)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Laserocarpum, a new genus of Apiaceae endemic to Greece
Acta Societatis Botanicorum Poloniae, 2019 Laserpitium pseudomeum is an endemic umbellifer of Greece occurring in the mountains of Sterea Ellas and northern Peloponnese. Molecular data indicate that it is not related to its putative congeners, but instead constitutes an isolated lineage.
Krzysztof Spalik +5 more
doaj +1 more source
A chemical evolution model for galaxy clusters [PDF]
, 2001 We develop a toy-model for the chemical evolution of the intracluster medium, polluted by the galactic winds from elliptical galaxies. The model follows the "galaxy formation history" of cluster galaxies, constrained by the observed luminosity function ...
Chiosi, C., Moretti, A., Portinari, L.
core +1 more source
, 2014 We review chemical evolution models developed for M31 as well as the abundance determinations available for this galaxy. Then we present a recent chemical evolution model for M31 including radial gas flows and galactic fountains along the disk, as well ...
Matteucci, F., Spitoni, E.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Astrophysical JournalWithin the Milky Way (MW), younger stellar populations exhibit steeper (more negative) metallicity radial gradients; the origin of this trend remains debated. The FIRE-2 cosmological simulations of MW-mass galaxies show the same trend as the MW, which in
Russell L. Graf +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Bacterial symbionts support larval sap feeding and adult folivory in (semi-)aquatic reed beetles
Nature Communications, 2020 Symbiotic microbes in insects can enable their hosts to access untapped nutritional resources. Here, the authors show that symbiotic bacteria in reed beetles can provide essential amino acids to sap-feeding larvae and help leaf-feeding adults to degrade ...
Frank Reis +8 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in Endocrinology, 2018 The nervous system of the free-living planktonic larvae of sea urchins is relatively “simple,” but sufficiently complex to enable sensing of the environment and control of swimming and feeding behaviors.
Natalie J. Wood +10 more
doaj +1 more source