Results 61 to 70 of about 477,042 (311)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frontiers in Immunology, 2023 Inflammatory response triggered by innate immunity can act to protect against microorganisms that behave as pathogens, with the aim to restore the homeostatic state between host and beneficial microbes.
Assunta Liberti +10 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
BMC Biology, 2018 Reinvestigation of the raw data revealed an unfortunate error in Ugelvig et al. 2008 [1].
Line V. Ugelvig +5 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Chemical transport model ozone simulations for spring 2001 over the western Pacific : comparisons with TRACE-P lidar, ozonesondes, and Total Ozone Mapping Spectrometer columns [PDF]
, 2003 Two closely related chemical transport models (CTMs) employing the same high-resolution meteorological data (similar to180 km x similar to180 km x similar to600 m) from the European Centre for Medium-Range Weather Forecasts are used to simulate the ozone
Isaksen, I S A +18 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Chemical evolution of galaxies
, 2012 The term “chemical evolution of galaxies” refers to the evolution of abundances of chemical species in galaxies, which is due to nuclear processes occurring in stars and to gas flows into and out of galaxies.
Matteucci, Francesca +1 more
core +1 more source
Disk evolution, element abundances and cloud properties of young gas giant planets [PDF]
, 2014 ChHc and PBR highlights financial support of the European Community under the FP7 program by an ERC starting grant. PW, IK, and WFT acknowledge funding from the European Union Seventh Framework Programme FP7-2011 under grant agreement No.
Kamp, I. +19 more
core +1 more source