Results 61 to 70 of about 1,651,932 (286)
Galactic chemical evolution [PDF]
In this paper we review the current ideas about the formation of our Galaxy. In particular, the main ingredients necessary to build chemical evolution models (star formation, initial mass function and stellar yields) are described and discussed. A critical discussion about the main observational constraints available is also presented.
Gabriele Cescutti, Cristina Chiappini
openaire +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Reinvestigation of the raw data revealed an unfortunate error in Ugelvig et al. 2008 [1].
Line V. Ugelvig +5 more
doaj +1 more source
Massive star evolution in close binaries:conditions for homogeneous chemical evolution
We investigate the impact of tidal interactions, before any mass transfer, on various properties of the stellar models. We study the conditions for obtaining homogeneous evolution triggered by tidal interactions, and for avoiding any Roche lobe overflow ...
Eggenberger, P. +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Galactic and Cosmic Chemical Evolution with Hypernovae
We provide new nucleosynthesis yields depending on metallicity and energy (i.e., (normal supernovae and hypernovae), and show the evolution of heavy element abundances from C to Zn in the solar neighborhood.
Kobayashi, Chiaki
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
`Pure' Supernovae and Accelerated Expansion of the Universe
A special class of type Ia supernovae that is not subject to ordinary and additional intragalactic gray absorption and chemical evolution has been identified.
A. Aguirre +26 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

