Results 51 to 60 of about 477,042 (311)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

High-throughput library transgenesis in Caenorhabditis elegans via Transgenic Arrays Resulting in Diversity of Integrated Sequences (TARDIS)

eLife, 2023
High-throughput transgenesis using synthetic DNA libraries is a powerful method for systematically exploring genetic function. Diverse synthesized libraries have been used for protein engineering, identification of protein–protein interactions ...
Zachary C Stevenson, Megan J Moerdyk-Schauwecker, Stephen A Banse, Dhaval S Patel, Hang Lu, Patrick C Phillips   +5 more
doaj   +1 more source

Evolution of the Cannabinoid and Terpene Content during the Growth of Cannabis sativa Plants from Different Chemotypes

, 2016
The evolution of major cannabinoids and terpenes during the growth of Cannabis sativa plants was studied. In this work, seven different plants were selected: three each from chemotypes I and III and one from chemotype II.
Schibano, Daniele, Simsir, Yilmaz, Etxebarria, Nestor, Soydaner, Umut, Navarro, Patricia, Usobiaga, Aresatz, Chemical Biology and Drug Discovery, Aizpurua-Olaizola, Oier, Öztürk, Ekin, Sub Chemical pharmacology   +9 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Refueling the Magic Furnace: Kilonova 2017 Rewrites the Story of Element Origins

Journal of Big History, 2018
For more than half a century, we have understood element creation in the stars—described in Marcus Chown’s colorful image as “the magic furnace.” From 1958 until 2017, supernova explosions were thought to be the primary site of element creation above ...
Barry Woods
doaj   +1 more source

Chemical evolution of Seyfert galaxies

, 2008
We computed the chemical evolution of Seyfert galaxies, residing in spiral bulges, based on an updated model for the Milky Way bulge with updated calculations of the Galactic potential and of the feedback from the central supermassive black hole (BH ...
CIOTTI, LUCA, Francesca Matteucci, S. K. Ballero, F. Matteucci, Silvia K. Ballero, Luca Ciotti   +5 more
core   +1 more source

An intercomparison and evaluation of aircraft-derived and simulated CO from seven chemical transport models during the TRACE-P experiment [PDF]

, 2003
Four global scale and three regional scale chemical transport models are intercompared and evaluated during NASA's Transport and Chemical Evolution over the Pacific (TRACE-P) experiment.
Palmer, P I, Kiley, C M, Pierce, R. B., Palmer, P. I., Wild, O., Jacob, D. J., Carmichael, G R, Fuelberg, H. E., Pickering, K. E., Logan, J. A., Kiley, C. M., Fairlie, T D, Streets, D G, Streets, D. G., Allen, D J, Pickering, K E, Jacob, D J, Shaack, T. K., Fuelberg, H E, Pierce, R B, Sachse, G. W., Allen, D. J., Sachse, G W, Mari, C., Tang, Y H, Mari, C, Logan, J A, Shaack, T K, Wild, O, Carmichael, G. R., Fairlie, T. D., Tang, Y. H.   +31 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Four terpene synthases contribute to the generation of chemotypes in tea tree (Melaleuca alternifolia)

BMC Plant Biology, 2017
Background Terpene rich leaves are a characteristic of Myrtaceae. There is significant qualitative variation in the terpene profile of plants within a single species, which is observable as “chemotypes”.
Amanda Padovan, Andras Keszei, Yasmin Hassan, Sandra T. Krause, Tobias G. Köllner, Jörg Degenhardt, Jonathan Gershenzon, Carsten Külheim, William J. Foley   +8 more
doaj   +1 more source

Importance of understanding variable and transient energy demand in large multi-product industrial plants for process integration

, 2011
There have been some news releases claiming that Professor Henle in Germany has found the chemical identity of UMF, and that in future chemical analysis will be used instead of assays of antibacterial activity to indicate the level of UMF in manuka honey.
Walmsley, Michael R.W., Morrison, Andrew S., Atkins, Martin John, Neale, James R.   +3 more
core   +1 more source