Results 1 to 10 of about 14,980 (199)

Improved haplotype resolution of highly duplicated MHC genes in a long-read genome assembly using MiSeq amplicons [PDF]

PeerJ, 2023
Long-read sequencing offers a great improvement in the assembly of complex genomic regions, such as the major histocompatibility complex (MHC) region, which can contain both tandemly duplicated MHC genes (paralogs) and high repeat content.
Samantha Mellinger, Martin Stervander, Max Lundberg, Anna Drews, Helena Westerdahl   +4 more
doaj   +2 more sources

The metabolic network of the last bacterial common ancestor

Communications Biology, 2021
Joana C. Xavier, Rebecca E. Gerhards and colleagues reconstruct the habitat and lifestyle of the last bacterial common ancestor (LBCA) through the construction of the metabolic network and gene tree analysis of 146 LCBA protein families.
Joana C. Xavier, Rebecca E. Gerhards, Jessica L. E. Wimmer, Julia Brueckner, Fernando D. K. Tria, William F. Martin   +5 more
doaj   +1 more source

Genomic sequence capture of Plasmodium relictum in experimentally infected birds

Parasites & Vectors, 2022
Background Sequencing parasite genomes in the presence of host DNA is challenging. Sequence capture can overcome this problem by using RNA probes that hybridize with the parasite DNA and then are removed from solution, thus isolating the parasite DNA for
Vincenzo A. Ellis, Victor Kalbskopf, Arif Ciloglu, Mélanie Duc, Xi Huang, Abdullah Inci, Staffan Bensch, Olof Hellgren, Vaidas Palinauskas   +8 more
doaj   +1 more source

Genomics and transcriptomics of epizoic Seisonidea (Rotifera, syn. Syndermata) reveal strain formation and gradual gene loss with growing ties to the host

BMC Genomics, 2021
Background Seisonidea (also Seisonacea or Seisonidae) is a group of small animals living on marine crustaceans (Nebalia spec.) with only four species described so far. Its monophyletic origin with mostly free-living wheel animals (Monogononta, Bdelloidea)
Katharina M. Mauer, Hanno Schmidt, Marco Dittrich, Andreas C. Fröbius, Sören Lukas Hellmann, Hans Zischler, Thomas Hankeln, Holger Herlyn   +7 more
doaj   +1 more source

Microbial Community Structure Driven by a Volcanic Gradient in Glaciers of the Antarctic Archipelago South Shetland

Microorganisms, 2021
It has been demonstrated that the englacial ecosystem in volcanic environments is inhabited by active bacteria. To know whether this result could be extrapolated to other Antarctic glaciers and to study the populations of microeukaryotes in addition to ...
Eva García-Lopez, Sandra Serrano, Miguel Angel Calvo, Sonia Peña Perez, Silvia Sanchez-Casanova, Laura García-Descalzo, Cristina Cid   +6 more
doaj   +1 more source

Linking molecular evolution to molecular grafting [PDF]

Journal of Biological Chemistry, 2021
Molecular grafting is a strategy for the engineering of molecular scaffolds into new functional agents, such as next-generation therapeutics. Despite its wide use, studies so far have focused almost exclusively on demonstrating its utility rather than understanding the factors that lead to either poor or successful grafting outcomes.
Conan K. Wang, David J. Craik
openaire   +3 more sources

Evaluation of intra- and interspecific divergence of satellite DNA sequences by nucleotide frequency calculation and pairwise sequence comparison

Biological Procedures Online, 2003
Satellite DNA sequences are known to be highly variable and to have been subjected to concerted evolution that homogenizes member sequences within species.
Kato Mikio
doaj   +1 more source

Conspicuousness, phylogenetic structure, and origins of Müllerian mimicry in 4000 lycid beetles from all zoogeographic regions

Scientific Reports, 2021
Biologists have reported on the chemical defences and the phenetic similarity of net-winged beetles (Coleoptera: Lycidae) and their co-mimics. Nevertheless, our knowledge has remained fragmental, and the evolution of mimetic patterns has not been studied
Michal Motyka, Dominik Kusy, Michal Masek, Matej Bocek, Yun Li, R. Bilkova, Josef Kapitán, Takashi Yagi, Ladislav Bocak   +8 more
doaj   +1 more source

Realistic Gene Transfer to Gene Duplication Ratios Identify Different Roots in the Bacterial Phylogeny Using a Tree Reconciliation Method

Life, 2022
The rooting of phylogenetic trees permits important inferences about ancestral states and the polarity of evolutionary events. Recently, methods that reconcile discordance between gene-trees and species-trees—tree reconciliation methods—are becoming ...
Nico Bremer, Michael Knopp, William F. Martin, Fernando D. K. Tria   +3 more
doaj   +1 more source

Cancer Molecular Evolution [PDF]

Journal of Molecular Evolution, 2015
By far, the majority of studies in molecular evolution have focused on genetic change across one or more generations. Much less is known about the genetic changes that occur during the life time of an individual, or somatic evolution, of which cancer is probably the best-known example.
openaire   +4 more sources