Results 91 to 100 of about 6,342,096 (314)

The Origin and Evolution of Viruses as Molecular Organisms [PDF]

open access: yes, 2009
Viruses are the most abundant life forms and the repertoire of viral genes is greater than that of cellular genes. It is also evident that viruses have played a major role in driving cellular evolution, and yet, viruses are not part of mainstream biology,
Claudiu I. Bandea
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The distributions of protein coding genes within chromatin domains in relation to human disease

open access: yesEpigenetics & Chromatin, 2019
Background Our understanding of the nuclear chromatin structure has increased hugely during the last years mainly as a consequence of the advances in chromatin conformation capture methods like Hi-C.
Enrique M. Muro   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Molecular evolution in Hawaiian drosophilids

open access: yesTrends in Ecology & Evolution, 1987
Uploaded by Plazi for TaxoDros. We do not have abstracts.
R, Desalle, J A, Hunt
openaire   +2 more sources

Deciphering the Relationship between Mating System and the Molecular Evolution of the Pheromone and Receptor Genes in Neurospora

open access: yes, 2012
Here, we present a study of the molecular evolution of the pheromone receptor genes (pre-1 and pre-2) in Neurospora taxa with different mating systems.
Nygren, Kristiina,   +2 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Quantifying Phylogenetic Conservation in Protein Molecular Evolution

open access: yes, 2006
This dissertation examines the problem of quantifying amino acid conservation in proteins molecular evolution. Ideally, this conservation is quantified by inferring the rate of evolution at each amino acid site of a multiple-alignment.
Fernandes, Andrew Dellano
core  

EL BORO Y EL MUNDO ARN

open access: yesRevista de Química, 2019
Además de sus usos comerciales, los minerales de boro han sido de interés para los investigadores que buscan encontrar una explicación a como se originó la vida en la Tierra.
Roberto Laos, Steven Benner
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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