Results 71 to 80 of about 4,105,755 (293)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Evolution equation for quantum coherence [PDF]

open access: yes
Quantum coherence plays an important role in quantum resource theory, which is strongly related with entanglement. Similar to the entanglement evolution equation, we find the coherence evolution equation of quantum states through fully and strictly ...
Zhao, Xinzhi   +4 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Evolution equation for elastic scattering of hadrons

open access: yesEuropean Physical Journal C: Particles and Fields, 2022
We turn high energy elastic scattering of hadrons into an initial value problem using an evolution equation based on the Regge Field Theory, which has a form of the complex nonlinear reaction–diffusion equation, with time being played by the logarithm of
Hiren Kakkad   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Neumann problem on the semi-line for the Burgers equation [PDF]

open access: yes, 2011
In this article, the Neumann problem on the semi-line for the Burgers equation is considered. The problem is reduced to a nonlinear integral equation in one independent variable, whose unique solution is proven to exist for small time.
Sommacal, Matteo, de Lillo, Silvana
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

TOPICAL REVIEW: Phase-field modeling of microstructure evolutions in magnetic materials

open access: yesScience and Technology of Advanced Materials, 2008
Recently, the phase-field method has been extended and utilized across many fields of materials science. Since this method can incorporate, systematically, the effect of the coherency induced by lattice mismatch and the applied stress as well as the ...
Toshiyuki Koyama
doaj  

On the evolution equation for magnetic geodesics [PDF]

open access: yesCalculus of Variations and Partial Differential Equations, 2009
In this paper we prove the existence of long time solutions for the parabolic equation for closed magnetic geodesics.
openaire   +2 more sources

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