Results 71 to 80 of about 218,478 (262)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Optimal control for systems governed by parabolic equations without initial conditions with controls in the coefficients

Electronic Journal of Differential Equations, 2017
We consider an optimal control problem for systems described by a Fourier problem for parabolic equations. We prove the existence of solutions, and obtain necessary conditions of the optimal control in the case of final observation when the control ...
Mykola Bokalo, Andrii Tsebenko
doaj  

The Existence and Uniqueness of Mild Solutions for Fuzzy Hilfer Fractional Evolution Equations with Non-Local Conditions

Axioms
In this paper, we investigate a fuzzy Hilfer fractional evolution equation of type ...
Kholoud N. Alharbi, Sanaa Alotaibi
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Integrable Anisotropic Evolution Equations on a Sphere

Symmetry, Integrability and Geometry: Methods and Applications, 2005
V.V. Sokolov's modifying symmetry approach is applied to anisotropic evolution equations of the third order on the n-dimensional sphere. The main result is a complete classification of such equations.
Anatoly G. Meshkov, Maxim Ju. Balakhnev
doaj  

On the evolution equation for magnetic geodesics [PDF]

Calculus of Variations and Partial Differential Equations, 2009
In this paper we prove the existence of long time solutions for the parabolic equation for closed magnetic geodesics.
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Monotone iterative method for retarded evolution equations involving nonlocal and impulsive conditions

Electronic Journal of Differential Equations, 2020
In this article, we apply the perturbation technique and monotone iterative method in the presence of the lower and the upper solutions to discuss the existence of the minimal and maximal mild solutions to the retarded evolution equations involving ...
Xuping Zhang, Pengyu Chen, Yongxiang Li
doaj  

The chaotic effects in a nonlinear QCD evolution equation

Nuclear Physics B, 2016
The corrections of gluon fusion to the DGLAP and BFKL equations are discussed in a united partonic framework. The resulting nonlinear evolution equations are the well-known GLR–MQ–ZRS equation and a new evolution equation.
Wei Zhu, Zhenqi Shen, Jianhong Ruan
doaj   +1 more source

Study of the soliton propagation of the fractional nonlinear type evolution equation through a novel technique. [PDF]

PLoS One, 2023
Zaman UHM, Arefin MA, Akbar MA, Uddin MH.   +3 more
europepmc   +1 more source