Results 91 to 100 of about 984,564 (290)

The membrane receptors that appeared before their ligand: The different proposed scenarios.

PLoS ONE, 2020
The interactions between membrane receptors and their endogenous ligands are key interactions in organisms. Recently, we have shown that a high number of genes encoding human receptors appeared at the same moment as their ligand in the animal tree of ...
Anna Grandchamp, Philippe Monget
doaj   +1 more source

Mild Velocity Dispersion Evolution of Spheroid-like Massive Galaxies since z~2

, 2009
Making use of public spectra from Cimatti et al (2008), we measure for the first time the velocity dispersion of spheroid-like massive (M_star ~ 10^11 M_sun) galaxies at z ~ 1.6.
A. Javier Cenarro, Ayres, Beasley, Bernardi, Blanton, Blanton, Buitrago, Cardiel, Churchill, Daddi, Damjanov, Fan, Ferreras, Giavalisco, González, Gregg, Heap, Hopkins, Ignacio Trujillo, Khochfar, Naab, Pérez-González, Ravindranath, Ravindranath, Sérsic, Toft, Trujillo, Trujillo, van der Wel, van der Wel, van Dokkum, Zirm   +31 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

A resilience evolution model of urban lifeline systems during operation based on performance state transitions

Journal of Safety Science and Resilience
To better understand the resilience evolution dynamics of urban lifeline systems over extended operational periods, this study introduces a model inspired by the susceptible-infected-recovered (SIR) model, which is traditionally used to simulate ...
Dongyue Zhao, Qian Chen, Xiaolong Zhao, Yunhe Tong, Changkun Chen, Shijie Xia   +5 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Office of exploration overview [PDF]

The NASA Office of Exploration case studies for FY89 are reviewed with regard to study ground rules and constraints. Three study scenarios are presented: lunar evolution, Mars evolution, and Mars expedition with emphasis on the key mission ...
Alred, John
core   +1 more source

Evolutionary Models of Super-Earths and Mini-Neptunes Incorporating Cooling and Mass Loss

, 2015
We construct models of the structural evolution of super-Earth- and mini-Neptune-type exoplanets with hydrogen-helium envelopes, incorporating radiative cooling and XUV-driven mass loss.
Burrows, Adam S., Howe, Alex R.
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source